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An in vitro and in vivo evaluation of new potential trans-sialidase inhibitors of Trypanosoma cruzi predicted by a computational drug repositioning method
por
Lara-Ramirez, E.E.
,
López
-
Cedillo
,
J.C
.
,
Nogueda-Torres, B.
,
Kashif, M.
,
Garcia-Perez, C.
,
Bocanegra-Garcia, V.
,
Agusti, R.
,
Uhrig, M.L.
,
Rivera, G.
Aportado por:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
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JOUR
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Synthesis, molecular docking and biological evaluation of novel phthaloyl derivatives of 3-amino-3-aryl propionic acids as inhibitors of Trypanosoma cruzi trans-sialidase
por
Kashif, M.
,
Chacón-Vargas, K.F.
,
López
-
Cedillo
,
J.C
.
,
Nogueda-Torres, B.
,
Paz-González, A.D.
,
Ramírez-Moreno, E.
,
Agusti, R.
,
Uhrig, M.L.
,
Reyes-Arellano, A.
,
Peralta-Cruz, J.
,
Ashfaq, M.
,
Rivera, G.
Aportado por:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
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JOUR
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Materias Relacionadas
Article
Glycoproteins
Neuraminidase
Structure-Activity Relationship
Trans-sialidase
Trypanosoma cruzi
antagonists and inhibitors
chemistry
controlled study
enzyme inhibition
glycoprotein
nonhuman
sialidase
sialidase inhibitor
sialylation
structure activity relation
trans-sialidase
2 [2 carboxy 1 (2 nitrophenyl)ethyl] 1,3 dioxoisoindoline 5 carboxylic acid
2 [2 carboxy 1 (4 ethylphenyl)ethyl] 1,3 dioxoisoindoline 5 carboxylic acid
2 [2 carboxy 1 (4 hydroxyphenyl)ethyl] 1,3 dioxoisoindoline 5 carboxylic acid
2 [2 carboxy 1 (4 methoxyphenyl)ethyl] 1,3 dioxoisoindoline 5 carboxylic acid
2 [2 carboxy 1 (4 nitrophenyl)ethyl] 1,3 dioxoisoindoline 5 carboxylic acid
2 [2 carboxy 1 (4 tolyl)ethyl] 1,3 dioxoisoindoline 5 carboxylic acid
3 (1,3 dioxoisoindolin 2 yl) 3 (4 ethylphenyl)propanoic acid
3 (1,3 dioxoisoindolin 2 yl) 3 (4 hydroxyphenyl)propanoic acid
3 (1,3 dioxoisoindolin 2 yl) 3 (4 methoxyphenyl)propanoic acid
3 (1,3 dioxoisoindolin 2 yl) 3 (4 nitrophenyl)propanoic acid
3 (1,3 dioxoisoindolin 2 yl) 3 (4 tolyl)propanoic acid
3 (4 ethylphenyl) 3 (5 methyl 1,3 dioxoisoindolin 2 yl)propanoic acid
3 (4 hydroxyphenyl) 3 (5 methyl 1,3 dioxoisoindolin 2 yl)propanoic acid
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