structure activity relation article 154 nonhuman 148 unclassified drug 144 controlled study 110 Structure-Activity Relationship 104 Animals 98 human 96 Humans 84 priority journal 82 chemistry 80 drug synthesis 66 metabolism 66 animal 62 animal cell 58 drug structure 56 in vitro study 50 Article 48 chemical structure 44 Models, Molecular 40 structure analysis 36 synthesis 36 molecular dynamics 34 dose response 32 drug effects 32 drug screening 32 molecular model 32 Molecular Structure 30 Trypanosoma cruzi 30 binding affinity 30