RSUME is implicated in HIF-1-induced VEGF-A production in pituitary tumour cells

The recently cloned small RWD-domain containing protein RSUME was shown to increase protein levels of hypoxia-inducible factor-1α (HIF-1α). The latter is the oxygen-regulated subunit of HIF-1, the most important transcription factor of the cellular adaptive processes to hypoxic conditions. It is als...

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Detalles Bibliográficos
Autores principales: Shan, B., Gerez, J., Haedo, M., Fuertes, M., Theodoropoulou, M., Buchfelder, M., Losa, M., Stalla, G.K., Arzt, E., Renner, U.
Formato: JOUR
Materias:
cobalt chloride
hypoxia inducible factor 1alpha
messenger RNA
protein
protein RSUME
small interfering RNA
unclassified drug
vasculotropin A
cobalt
HIF1A protein, human
RSUME protein, human
transcription factor
VEGFA protein, human
article
cancer cell culture
cell nucleus
controlled study
correlation analysis
down regulation
human
human cell
human tissue
hypophysis adenoma
hypoxia
protein expression
protein function
protein induction
protein secretion
protein transport
RNA interference
upregulation
adenoma
animal
anoxia
biosynthesis
genetics
hypophysis tumor
metabolism
mouse
neovascularization (pathology)
tumor cell culture
tumor cell line
Adenoma
Animals
Anoxia
Cell Line, Tumor
Cobalt
Humans
Hypoxia-Inducible Factor 1, alpha Subunit
Mice
Neovascularization, Pathologic
Pituitary Neoplasms
RNA, Messenger
Transcription Factors
Tumor Cells, Cultured
Vascular Endothelial Growth Factor A
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_13510088_v19_n1_p13_Shan
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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