Mitochondrial biosynthesis of cholesterol in leydig cells from rat testis

The subcellular location of some enzymes responsible for cholesterol biosynthesis was studied in metrizamide-purified rat Leydig cells.The highest activity of 3-hydroxy-3-methyl glutaryl coenzyme A reductase (HMG-CoA reductase), a key regulatory enzyme in the cholesterol pathway, was associated with...

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Detalles Bibliográficos
Autores principales: Pignataro, O.P., Radicella, J.P., Calvo, J.C., Charreau, E.H.
Formato: JOUR
Materias:
cholesterol biosynthesis
HMG-CoA reductase
Leydig cell
hydroxymethylglutaryl coenzyme a reductase
radioisotope
acetyl coenzyme a c 14
animal experiment
biological model
cholesterol synthesis
endocrine system
leydig cell
male genital system
mitochondrion
nonhuman
rat
Acetates
Acetyl Coenzyme A
Animal
Cell Compartmentation
Cholesterol
Hydroxymethylglutaryl CoA Reductases
Leydig Cells
Male
Mitochondria
Rats
Support, Non-U.S. Gov't
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03037207_v33_n1_p53_Pignataro
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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