Design, synthesis, and biological evaluation of new growth inhibitors of Trypanosoma cruzi (epimastigotes)

As a continuation of our project aimed at the search for new chemotherapeutic agents against Chagas' disease, several drugs structurally related to the insect growth regulator Fenoxycarb and the naturally occurring juvenfie hormone of insects were designed, synthesized, and evaluated as antipro...

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Detalles Bibliográficos
Autores principales:	Schvartzapel, A.J., Zhong, L., Docampo, R., Rodriguez, J.B., Gros, E.G.
Formato:	JOUR
Materias:	3,7 dimethylocta 2,6 dien 1 yl ethylcarbamate 3,7 dimethylocta 2,6 dien 1 yl tetrahydro 2h pyran 2 yl ether 3,7,11 trimethyldodeca 2,6,10 trien 1 yl ethylcarbamate 3,7,11 trimethyldodeca 2,6,10 trien 1 yl tetrahydro 2h pyran 2 yl ether 4 benzoylphenyl prop 2 en 1 yl ether benznidazole fenoxycarb isoprenoid nifurtimox unclassified drug article chagas disease drug design drug synthesis epimastigote structure activity relation trypanosoma cruzi Animals Drug Design Magnetic Resonance Spectroscopy Mass Spectrometry Molecular Structure Spectrophotometry, Infrared Trypanocidal Agents Trypanosoma cruzi
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00222623_v40_n15_p2314_Schvartzapel
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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