article drug synthesis trypanosoma cruzi Animals Trypanocidal Agents Trypanosoma cruzi chagas disease drug design epimastigote fenoxycarb nifurtimox unclassified drug 3,7 dimethylocta 2,6 dien 1 yl ethylcarbamate 3,7 dimethylocta 2,6 dien 1 yl tetrahydro 2h pyran 2 yl ether 3,7,11 trimethyldodeca 2,6,10 trien 1 yl ethylcarbamate 3,7,11 trimethyldodeca 2,6,10 trien 1 yl tetrahydro 2h pyran 2 yl ether 4 benzoylphenyl prop 2 en 1 yl ether 4 phenoxyphenoxyethyl thiocyanate Drug Design Drug Evaluation, Preclinical Magnetic Resonance Spectroscopy Mass Spectrometry Molecular Structure Nifurtimox Phenyl Ethers Spectrophotometry, Infrared Structure-Activity Relationship Thiocyanates benznidazole carbamic acid derivative