Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme
Angiotensin converting enzyme was detectable in rat pineal gland and exhibited a circadian rhythm in activity with maximum at the end of the light phase of daily photoperiod. Superior cervical ganglionectomy (SCGx) or exposure to light for 6 days increased enzyme activity and obliterated morning-eve...
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Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00068993_v236_n1_p216_Nahmod |
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todo:paper_00068993_v236_n1_p216_Nahmod2023-10-03T14:05:20Z Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme Nahmod, V.E. Balda, M.S. Pirola, C.J. Finkielman, S. Gejman, P.V. Cardinali, D.P. angiotensin angiotensin converting enzyme Captopril circadian rhythms norepinephrine pineal gland superior cervical ganglia captopril dipeptidyl carboxypeptidase isoprenaline noradrenalin sq 14,225 unclassified drug animal experiment autonomic nervous system circadian rhythm endocrine system pineal body rat superior cervical ganglion Animals Circadian Rhythm Ganglia, Sympathetic Isoproterenol Light Male Norepinephrine Peptidyl-Dipeptidase A Pineal Gland Rats Rats, Inbred Strains Receptors, Adrenergic, beta Spinal Cord Angiotensin converting enzyme was detectable in rat pineal gland and exhibited a circadian rhythm in activity with maximum at the end of the light phase of daily photoperiod. Superior cervical ganglionectomy (SCGx) or exposure to light for 6 days increased enzyme activity and obliterated morning-evening differences, whereas injection of the β-agonist isoproterenol depressed the high values observed in SCGx animals. These results indicate that angiotensin converting enzyme in the pineal gland is under negative control by the norepinephrine released from pineal sympathetic nerves. © 1982. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00068993_v236_n1_p216_Nahmod |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
angiotensin angiotensin converting enzyme Captopril circadian rhythms norepinephrine pineal gland superior cervical ganglia captopril dipeptidyl carboxypeptidase isoprenaline noradrenalin sq 14,225 unclassified drug animal experiment autonomic nervous system circadian rhythm endocrine system pineal body rat superior cervical ganglion Animals Circadian Rhythm Ganglia, Sympathetic Isoproterenol Light Male Norepinephrine Peptidyl-Dipeptidase A Pineal Gland Rats Rats, Inbred Strains Receptors, Adrenergic, beta Spinal Cord |
spellingShingle |
angiotensin angiotensin converting enzyme Captopril circadian rhythms norepinephrine pineal gland superior cervical ganglia captopril dipeptidyl carboxypeptidase isoprenaline noradrenalin sq 14,225 unclassified drug animal experiment autonomic nervous system circadian rhythm endocrine system pineal body rat superior cervical ganglion Animals Circadian Rhythm Ganglia, Sympathetic Isoproterenol Light Male Norepinephrine Peptidyl-Dipeptidase A Pineal Gland Rats Rats, Inbred Strains Receptors, Adrenergic, beta Spinal Cord Nahmod, V.E. Balda, M.S. Pirola, C.J. Finkielman, S. Gejman, P.V. Cardinali, D.P. Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme |
topic_facet |
angiotensin angiotensin converting enzyme Captopril circadian rhythms norepinephrine pineal gland superior cervical ganglia captopril dipeptidyl carboxypeptidase isoprenaline noradrenalin sq 14,225 unclassified drug animal experiment autonomic nervous system circadian rhythm endocrine system pineal body rat superior cervical ganglion Animals Circadian Rhythm Ganglia, Sympathetic Isoproterenol Light Male Norepinephrine Peptidyl-Dipeptidase A Pineal Gland Rats Rats, Inbred Strains Receptors, Adrenergic, beta Spinal Cord |
description |
Angiotensin converting enzyme was detectable in rat pineal gland and exhibited a circadian rhythm in activity with maximum at the end of the light phase of daily photoperiod. Superior cervical ganglionectomy (SCGx) or exposure to light for 6 days increased enzyme activity and obliterated morning-evening differences, whereas injection of the β-agonist isoproterenol depressed the high values observed in SCGx animals. These results indicate that angiotensin converting enzyme in the pineal gland is under negative control by the norepinephrine released from pineal sympathetic nerves. © 1982. |
format |
JOUR |
author |
Nahmod, V.E. Balda, M.S. Pirola, C.J. Finkielman, S. Gejman, P.V. Cardinali, D.P. |
author_facet |
Nahmod, V.E. Balda, M.S. Pirola, C.J. Finkielman, S. Gejman, P.V. Cardinali, D.P. |
author_sort |
Nahmod, V.E. |
title |
Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme |
title_short |
Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme |
title_full |
Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme |
title_fullStr |
Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme |
title_full_unstemmed |
Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme |
title_sort |
circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme |
url |
http://hdl.handle.net/20.500.12110/paper_00068993_v236_n1_p216_Nahmod |
work_keys_str_mv |
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1807318660772003840 |