Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme

Angiotensin converting enzyme was detectable in rat pineal gland and exhibited a circadian rhythm in activity with maximum at the end of the light phase of daily photoperiod. Superior cervical ganglionectomy (SCGx) or exposure to light for 6 days increased enzyme activity and obliterated morning-eve...

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Autores principales: Nahmod, V.E., Balda, M.S., Pirola, C.J., Finkielman, S., Gejman, P.V., Cardinali, D.P.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00068993_v236_n1_p216_Nahmod
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spelling todo:paper_00068993_v236_n1_p216_Nahmod2023-10-03T14:05:20Z Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme Nahmod, V.E. Balda, M.S. Pirola, C.J. Finkielman, S. Gejman, P.V. Cardinali, D.P. angiotensin angiotensin converting enzyme Captopril circadian rhythms norepinephrine pineal gland superior cervical ganglia captopril dipeptidyl carboxypeptidase isoprenaline noradrenalin sq 14,225 unclassified drug animal experiment autonomic nervous system circadian rhythm endocrine system pineal body rat superior cervical ganglion Animals Circadian Rhythm Ganglia, Sympathetic Isoproterenol Light Male Norepinephrine Peptidyl-Dipeptidase A Pineal Gland Rats Rats, Inbred Strains Receptors, Adrenergic, beta Spinal Cord Angiotensin converting enzyme was detectable in rat pineal gland and exhibited a circadian rhythm in activity with maximum at the end of the light phase of daily photoperiod. Superior cervical ganglionectomy (SCGx) or exposure to light for 6 days increased enzyme activity and obliterated morning-evening differences, whereas injection of the β-agonist isoproterenol depressed the high values observed in SCGx animals. These results indicate that angiotensin converting enzyme in the pineal gland is under negative control by the norepinephrine released from pineal sympathetic nerves. © 1982. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00068993_v236_n1_p216_Nahmod
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic angiotensin
angiotensin converting enzyme
Captopril
circadian rhythms
norepinephrine
pineal gland
superior cervical ganglia
captopril
dipeptidyl carboxypeptidase
isoprenaline
noradrenalin
sq 14,225
unclassified drug
animal experiment
autonomic nervous system
circadian rhythm
endocrine system
pineal body
rat
superior cervical ganglion
Animals
Circadian Rhythm
Ganglia, Sympathetic
Isoproterenol
Light
Male
Norepinephrine
Peptidyl-Dipeptidase A
Pineal Gland
Rats
Rats, Inbred Strains
Receptors, Adrenergic, beta
Spinal Cord
spellingShingle angiotensin
angiotensin converting enzyme
Captopril
circadian rhythms
norepinephrine
pineal gland
superior cervical ganglia
captopril
dipeptidyl carboxypeptidase
isoprenaline
noradrenalin
sq 14,225
unclassified drug
animal experiment
autonomic nervous system
circadian rhythm
endocrine system
pineal body
rat
superior cervical ganglion
Animals
Circadian Rhythm
Ganglia, Sympathetic
Isoproterenol
Light
Male
Norepinephrine
Peptidyl-Dipeptidase A
Pineal Gland
Rats
Rats, Inbred Strains
Receptors, Adrenergic, beta
Spinal Cord
Nahmod, V.E.
Balda, M.S.
Pirola, C.J.
Finkielman, S.
Gejman, P.V.
Cardinali, D.P.
Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme
topic_facet angiotensin
angiotensin converting enzyme
Captopril
circadian rhythms
norepinephrine
pineal gland
superior cervical ganglia
captopril
dipeptidyl carboxypeptidase
isoprenaline
noradrenalin
sq 14,225
unclassified drug
animal experiment
autonomic nervous system
circadian rhythm
endocrine system
pineal body
rat
superior cervical ganglion
Animals
Circadian Rhythm
Ganglia, Sympathetic
Isoproterenol
Light
Male
Norepinephrine
Peptidyl-Dipeptidase A
Pineal Gland
Rats
Rats, Inbred Strains
Receptors, Adrenergic, beta
Spinal Cord
description Angiotensin converting enzyme was detectable in rat pineal gland and exhibited a circadian rhythm in activity with maximum at the end of the light phase of daily photoperiod. Superior cervical ganglionectomy (SCGx) or exposure to light for 6 days increased enzyme activity and obliterated morning-evening differences, whereas injection of the β-agonist isoproterenol depressed the high values observed in SCGx animals. These results indicate that angiotensin converting enzyme in the pineal gland is under negative control by the norepinephrine released from pineal sympathetic nerves. © 1982.
format JOUR
author Nahmod, V.E.
Balda, M.S.
Pirola, C.J.
Finkielman, S.
Gejman, P.V.
Cardinali, D.P.
author_facet Nahmod, V.E.
Balda, M.S.
Pirola, C.J.
Finkielman, S.
Gejman, P.V.
Cardinali, D.P.
author_sort Nahmod, V.E.
title Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme
title_short Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme
title_full Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme
title_fullStr Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme
title_full_unstemmed Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme
title_sort circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme
url http://hdl.handle.net/20.500.12110/paper_00068993_v236_n1_p216_Nahmod
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AT finkielmans circadianrhythmandneuralregulationofratpinealangiotensinconvertingenzyme
AT gejmanpv circadianrhythmandneuralregulationofratpinealangiotensinconvertingenzyme
AT cardinalidp circadianrhythmandneuralregulationofratpinealangiotensinconvertingenzyme
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