Flagellin delays spontaneous human neutrophil apoptosis

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Neutrophils are short-lived cells that rapidly undergo apoptosis. However, their survival can be regulated by signals from the environment. Flagellin, the primary component of the bacterial flagella, is known to induce neutrophil activation. In this study we examined the ability of flagellin to modu...

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Detalles Bibliográficos
Autores principales: Salamone, G.V., Petracca, Y., Bass, J.I.F., Rumbo, M., Nahmod, K.A., Gabelloni, M.L., Vermeulen, M.E., Matteo, M.J., Geffner, J.R., Trevani, A.S.
Formato: Artículo publishedVersion
Lenguaje:Inglés
Publicado: 2010
Materias:
apoptosis
flagellin
neutrophil
2 (2 amino 3 methoxyphenyl)chromone
3 (4 methylphenylsulfonyl) 2 propenenitrile
4 (4 fluorophenyl) 2 (4 methylsulfinylphenyl) 5 (4 pyridyl)imidazole
caspase 3
I kappa B alpha
interleukin 8
mitogen activated protein kinase 1
mitogen activated protein kinase 3
mitogen activated protein kinase p38
phosphatidylinositol 3 kinase
protein kinase B
protein mcl 1
toll like receptor 5
wortmannin
immunoglobulin enhancer binding protein
myeloid cell leukemia sequence 1 protein
protein bcl 2
article
bacterium mutant
cell survival
controlled study
cytokine production
enzyme phosphorylation
flow cytometry
fluorescence microscopy
Helicobacter pylori
human
human cell
leukocyte activation
priority journal
protein degradation
protein expression
Salmonella typhimurium
signal transduction
wild type
cell culture
drug effect
enzymology
flagellum
immunology
metabolism
physiology
salmonellosis
Apoptosis
Caspase 3
Cell Survival
Cells, Cultured
Flagella
Flagellin
Humans
MAP Kinase Signaling System
Neutrophils
NF-kappa B
Proto-Oncogene Proteins c-bcl-2
Salmonella Infections
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00236837_v90_n7_p1049_Salamone
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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