Phytochemical composition and biological screening of two Lophophytum species
Lophophytum species are holoparasites that grow on tree roots. The objectives of the work were to explore the chemical composition of the tubers of two Lophophytum species and to analyze the antioxidant, anti-inflammatory and antilithiatic activity of their extracts using in vitro methods. The ch...
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| Autores principales: | , , , , |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
Universidad de Santiago de Chile
2024
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| Materias: | |
| Acceso en línea: | http://repositorio.unne.edu.ar/handle/123456789/55211 |
| Aporte de: |
| Sumario: | Lophophytum species are holoparasites that grow on tree roots. The objectives of the work
were to explore the chemical composition of the tubers of two Lophophytum species and to analyze the
antioxidant, anti-inflammatory and antilithiatic activity of their extracts using in vitro methods. The
chemical composition was determined by histochemical, phytochemical and TLC tests. In addition, the
profile of phenolic compounds was determined by HPLC-MS. The presence of secondary metabolites of
recognized activity was demonstrated. The results of the HPLC-MS/MS allowed the tentative
identification of catechin, luteolin and glycosides of eriodictyol, naringenin and luteolin in the extract of
Lophophytum leandri and eriodictyol, naringenin, luteolin and their glycosylated derivatives in
Lophophytum mirabile. The extracts showed promising antioxidant (DPPH, ABTS and β-carotene-
linoleic acid), anti-inflammatory (inhibition of 5-LOX) and anti-urolytic (by bioautographic TLC)
activity. It is noteworthy that these are the first results of the phytochemical composition and biological
activity of L. mirabile. However, in vivo studies are required to corroborate these activities. |
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