Phytochemical composition and biological screening of two Lophophytum species

Lophophytum species are holoparasites that grow on tree roots. The objectives of the work were to explore the chemical composition of the tubers of two Lophophytum species and to analyze the antioxidant, anti-inflammatory and antilithiatic activity of their extracts using in vitro methods. The ch...

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Detalles Bibliográficos
Autores principales: Torres, Carola Analía, Pérez Zamora, Cristina Marisel, Sato, Héctor Arnaldo, Núñez, María Beatriz, González, Ana María
Formato: Artículo
Lenguaje:en_US
Publicado: Universidad de Santiago de Chile 2024
Materias:
Holoparasites
Naringenin
Antioxidant
Anti-inflammatory
Antilithiatic
Holoparásitas
Naringenina
Antioxidante
Antiinflammatorio
Antilitiásico
Acceso en línea:http://repositorio.unne.edu.ar/handle/123456789/55211
Aporte de:
RIUNNE - Repositorio Institucional de la Universidad Nacional del Nordeste (UNNE) de Universidad Nacional del Nordeste
id I48-R184-123456789-55211
record_format dspace
spelling I48-R184-123456789-552112024-10-07T10:34:50Z Phytochemical composition and biological screening of two Lophophytum species Composición fitoquímica y cribado biológico de dos especies de Lophophytum Torres, Carola Analía Pérez Zamora, Cristina Marisel Sato, Héctor Arnaldo Núñez, María Beatriz González, Ana María Holoparasites Naringenin Antioxidant Anti-inflammatory Antilithiatic Holoparásitas Naringenina Antioxidante Antiinflammatorio Antilitiásico Lophophytum species are holoparasites that grow on tree roots. The objectives of the work were to explore the chemical composition of the tubers of two Lophophytum species and to analyze the antioxidant, anti-inflammatory and antilithiatic activity of their extracts using in vitro methods. The chemical composition was determined by histochemical, phytochemical and TLC tests. In addition, the profile of phenolic compounds was determined by HPLC-MS. The presence of secondary metabolites of recognized activity was demonstrated. The results of the HPLC-MS/MS allowed the tentative identification of catechin, luteolin and glycosides of eriodictyol, naringenin and luteolin in the extract of Lophophytum leandri and eriodictyol, naringenin, luteolin and their glycosylated derivatives in Lophophytum mirabile. The extracts showed promising antioxidant (DPPH, ABTS and β-carotene- linoleic acid), anti-inflammatory (inhibition of 5-LOX) and anti-urolytic (by bioautographic TLC) activity. It is noteworthy that these are the first results of the phytochemical composition and biological activity of L. mirabile. However, in vivo studies are required to corroborate these activities. Las especies de Lophophytum son holoparásitas que crecen en raíces de árboles. Los objetivos del trabajo fueron explorar la composición química del túber de dos especies de Lophophytum y analizar la actividad antioxidante, antiinflamatoria y antilitiásica de sus extractos usando métodos in vitro. La composición química se determinó mediante pruebas histoquímicas, fitoquímicas y por TLC. Además, se determinó el perfil de compuestos fenólicos por HPLC-MS/MS. Se demostró presencia de metabolitos secundarios de reconocida actividad. Los resultados del HPLC-MS/MS permitieron identificar tentativamente catequina, luteolina y glucósidos de eriodictiol, naringenina y luteolina en el extracto de Lophophytum leandri y eriodictiol, naringenina, luteolina y sus derivados glicosilados en Lophophytum mirabile. Los extractos mostraron prometedora actividad antioxidante (DPPH, ABTS y β-caroteno-ácido linoleico), antiinflammatoria (inhibición de la 5-LOX) y antiurolitiásica (por TLC bioautográfica). Es de destacar que estos son los primeros resultados de composición fitoquímica y actividad biológica de L. mirabile. Sin embargo, se requieren estudios in vivo para corroborar dichas actividades. 2024-09-09T15:56:58Z 2024-09-09T15:56:58Z 2021-11 Artículo Torres, Carola Analía, et al., 2021. Phytochemical composition and biological screening of two Lophophytum species. Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas. Santiago: Universidad de Santiago de Chile, vol. 20, no. 6, p. 598-610. ISSN 0717-7917. DOI: https://doi.org/10.37360/blacpma.21.20.6.43. 0717-7917 http://repositorio.unne.edu.ar/handle/123456789/55211 en_US https://doi.org/10.37360/blacpma.21.20.6.43 openAccess http://creativecommons.org/licenses/by-nc-nd/2.5/ar/ application/pdf p. 598-610 application/pdf Universidad de Santiago de Chile Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas, 2021, vol. 20, no. 6, p. 598-610.
institution Universidad Nacional del Nordeste
institution_str I-48
repository_str R-184
collection RIUNNE - Repositorio Institucional de la Universidad Nacional del Nordeste (UNNE)
language en_US
topic Holoparasites
Naringenin
Antioxidant
Anti-inflammatory
Antilithiatic
Holoparásitas
Naringenina
Antioxidante
Antiinflammatorio
Antilitiásico
spellingShingle Holoparasites
Naringenin
Antioxidant
Anti-inflammatory
Antilithiatic
Holoparásitas
Naringenina
Antioxidante
Antiinflammatorio
Antilitiásico
Torres, Carola Analía
Pérez Zamora, Cristina Marisel
Sato, Héctor Arnaldo
Núñez, María Beatriz
González, Ana María
Phytochemical composition and biological screening of two Lophophytum species
topic_facet Holoparasites
Naringenin
Antioxidant
Anti-inflammatory
Antilithiatic
Holoparásitas
Naringenina
Antioxidante
Antiinflammatorio
Antilitiásico
description Lophophytum species are holoparasites that grow on tree roots. The objectives of the work were to explore the chemical composition of the tubers of two Lophophytum species and to analyze the antioxidant, anti-inflammatory and antilithiatic activity of their extracts using in vitro methods. The chemical composition was determined by histochemical, phytochemical and TLC tests. In addition, the profile of phenolic compounds was determined by HPLC-MS. The presence of secondary metabolites of recognized activity was demonstrated. The results of the HPLC-MS/MS allowed the tentative identification of catechin, luteolin and glycosides of eriodictyol, naringenin and luteolin in the extract of Lophophytum leandri and eriodictyol, naringenin, luteolin and their glycosylated derivatives in Lophophytum mirabile. The extracts showed promising antioxidant (DPPH, ABTS and β-carotene- linoleic acid), anti-inflammatory (inhibition of 5-LOX) and anti-urolytic (by bioautographic TLC) activity. It is noteworthy that these are the first results of the phytochemical composition and biological activity of L. mirabile. However, in vivo studies are required to corroborate these activities.
format Artículo
author Torres, Carola Analía
Pérez Zamora, Cristina Marisel
Sato, Héctor Arnaldo
Núñez, María Beatriz
González, Ana María
author_facet Torres, Carola Analía
Pérez Zamora, Cristina Marisel
Sato, Héctor Arnaldo
Núñez, María Beatriz
González, Ana María
author_sort Torres, Carola Analía
title Phytochemical composition and biological screening of two Lophophytum species
title_short Phytochemical composition and biological screening of two Lophophytum species
title_full Phytochemical composition and biological screening of two Lophophytum species
title_fullStr Phytochemical composition and biological screening of two Lophophytum species
title_full_unstemmed Phytochemical composition and biological screening of two Lophophytum species
title_sort phytochemical composition and biological screening of two lophophytum species
publisher Universidad de Santiago de Chile
publishDate 2024
url http://repositorio.unne.edu.ar/handle/123456789/55211
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