Efficacy of Argentine propolis formulation for topical treatment of canine otitis externa

The therapeutic effects of Argentine propolis ear drop formulation on canine otitis externa were evaluated. Forty-eight dogs with symptoms of otitis externa were randomly assigned to double–blinded, controlled clinical trial to evaluate the efficacy of topical formulation with propolis versus a to...

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Autores principales: Lozina, Laura, Peichoto, María Elisa, Boehringer, Silvia Irene, Koscinczuk, Patricia, Granero, Gladys Ester, Acosta, Ofelia Cristina
Formato: Artículo
Lenguaje:Inglés
Publicado: Universidade Federal de Minas Gerais. Escola de Veterinária 2022
Materias:
Dog
Propolis
Glicerin-propylenglycol
Otitis externa
Cão
Própolis
Glicerina-propilenoglicol
Otite externa
Acceso en línea:http://repositorio.unne.edu.ar/handle/123456789/48889
Aporte de:
RIUNNE - Repositorio Institucional de la Universidad Nacional del Nordeste (UNNE) de Universidad Nacional del Nordeste
id I48-R184-123456789-48889
record_format dspace
institution Universidad Nacional del Nordeste
institution_str I-48
repository_str R-184
collection RIUNNE - Repositorio Institucional de la Universidad Nacional del Nordeste (UNNE)
language Inglés
topic Dog
Propolis
Glicerin-propylenglycol
Otitis externa
Cão
Própolis
Glicerina-propilenoglicol
Otite externa
spellingShingle Dog
Propolis
Glicerin-propylenglycol
Otitis externa
Cão
Própolis
Glicerina-propilenoglicol
Otite externa
Lozina, Laura
Peichoto, María Elisa
Boehringer, Silvia Irene
Koscinczuk, Patricia
Granero, Gladys Ester
Acosta, Ofelia Cristina
Efficacy of Argentine propolis formulation for topical treatment of canine otitis externa
topic_facet Dog
Propolis
Glicerin-propylenglycol
Otitis externa
Cão
Própolis
Glicerina-propilenoglicol
Otite externa
description The therapeutic effects of Argentine propolis ear drop formulation on canine otitis externa were evaluated. Forty-eight dogs with symptoms of otitis externa were randomly assigned to double–blinded, controlled clinical trial to evaluate the efficacy of topical formulation with propolis versus a topical placebo in the treatment of otitis externa. The propolis preparation and placebo were administrated into both external ear canals, twice daily for 14 days. Throughout the study, clinical examination and microbiological analysis of dogs ear exudates were made. The most frequent microorganisms isolated in culture media were: Malassezia pachydermatis (54.2%), Staphylococcus aureus (43.8%), coagulase- negative Staphylococcus (25.0%), Pseudomonas aeruginosa (20.8%), Candida albicans (18.8%), Proteus mirabilis (16.7%), Streptococcus spp. (16.7%), Enteroccocus faecalis (12.5%), Escherichia coli (12.5%), Staphylococcus intermedius (6.3%), Klebsiella spp. (4.2%), and Candida glabrata (2.1%). Whereas the control group did not recover from the infectious ear disease, the propolis preparation exhibited antimicrobial activity against most of the microorganisms isolated from samples of the treated group. In addition, no propolis-adverse effects were observed. This allowed propolis-treated patients to show a significant improvement of the clinical parameters. Thus, this new Argentine propolis ear drop formulation may be used for topical treatment of otitis externa in dogs.
format Artículo
author Lozina, Laura
Peichoto, María Elisa
Boehringer, Silvia Irene
Koscinczuk, Patricia
Granero, Gladys Ester
Acosta, Ofelia Cristina
author_facet Lozina, Laura
Peichoto, María Elisa
Boehringer, Silvia Irene
Koscinczuk, Patricia
Granero, Gladys Ester
Acosta, Ofelia Cristina
author_sort Lozina, Laura
title Efficacy of Argentine propolis formulation for topical treatment of canine otitis externa
title_short Efficacy of Argentine propolis formulation for topical treatment of canine otitis externa
title_full Efficacy of Argentine propolis formulation for topical treatment of canine otitis externa
title_fullStr Efficacy of Argentine propolis formulation for topical treatment of canine otitis externa
title_full_unstemmed Efficacy of Argentine propolis formulation for topical treatment of canine otitis externa
title_sort efficacy of argentine propolis formulation for topical treatment of canine otitis externa
publisher Universidade Federal de Minas Gerais. Escola de Veterinária
publishDate 2022
url http://repositorio.unne.edu.ar/handle/123456789/48889
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