Anti venom activity of medicinal plants from south America

The use of plants to subdue or reverse the effects of snakebite has long been recognized. Plant extracts were widely used as therapy for snakebite by South American traditional healers, and especially in tropical regions where plant resources are diverse and plentiful. Several medicinal plants ar...

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Autores principales: Dellacassa, Eduardo Santiago, Torres, Ana María, Ricciardi, Gabriela Ana Leticia, Camargo, Francisco José, Tressens, Sara Graciela, Ricciardi, Armando Ítalo Amadeo
Formato: parte de libro
Lenguaje:Inglés
Publicado: Academic Press 2021
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Acceso en línea:http://repositorio.unne.edu.ar/handle/123456789/28837
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id I48-R184-123456789-28837
record_format dspace
institution Universidad Nacional del Nordeste
institution_str I-48
repository_str R-184
collection RIUNNE - Repositorio Institucional de la Universidad Nacional del Nordeste (UNNE)
language Inglés
topic South American medicinal plants
Bothrops
Anti venom activity
spellingShingle South American medicinal plants
Bothrops
Anti venom activity
Dellacassa, Eduardo Santiago
Torres, Ana María
Ricciardi, Gabriela Ana Leticia
Camargo, Francisco José
Tressens, Sara Graciela
Ricciardi, Armando Ítalo Amadeo
Anti venom activity of medicinal plants from south America
topic_facet South American medicinal plants
Bothrops
Anti venom activity
description The use of plants to subdue or reverse the effects of snakebite has long been recognized. Plant extracts were widely used as therapy for snakebite by South American traditional healers, and especially in tropical regions where plant resources are diverse and plentiful. Several medicinal plants are also believed to have been used as a source ofsnakebite antidote. Reference to the use of plants as part of early indigenous ethnomedical practices appears in traditional drug recipesrecovered from chronicles of Spanish explorers and includesevidence that methods were passed on orally through generations. The most frequently encountered poisonous snake genera found in regions of South America include: Bothrops (jarara/ lanceheads), Crotalus(casabel/rattlesnakes), Lachesis(surucucú/bushmasters) and Micrurus (coral). Coralsnakes have very powerful venombut confrontation with thesesnakesisinfrequent because of their quiet and secretive character. A bibliographic revision helped usidentify more than one hundred seventy plants with anti-venom activity in South America. Most are identified using their common names, sometimes making it difficult to determinetheformal taxonomic name. Furthermore, the absence of availablereferences or other documentation to verify oreven designate a properscientific name continuesto pose a problem. There have been numerous attempts to study and characterize the anti-venom activity in native plants. We show that modern methods that provide unequivocal identification of active compounds together with in vitro and in vivo assays have enabled both evaluation and validation of ancestral knowledge. Among the pharmacologically active secondary metabolites isolated from plants, flavonoids are most frequently cited inhibiting phospholipases, lipoxygenases and metalloproteases.
format parte de libro
author Dellacassa, Eduardo Santiago
Torres, Ana María
Ricciardi, Gabriela Ana Leticia
Camargo, Francisco José
Tressens, Sara Graciela
Ricciardi, Armando Ítalo Amadeo
author_facet Dellacassa, Eduardo Santiago
Torres, Ana María
Ricciardi, Gabriela Ana Leticia
Camargo, Francisco José
Tressens, Sara Graciela
Ricciardi, Armando Ítalo Amadeo
author_sort Dellacassa, Eduardo Santiago
title Anti venom activity of medicinal plants from south America
title_short Anti venom activity of medicinal plants from south America
title_full Anti venom activity of medicinal plants from south America
title_fullStr Anti venom activity of medicinal plants from south America
title_full_unstemmed Anti venom activity of medicinal plants from south America
title_sort anti venom activity of medicinal plants from south america
publisher Academic Press
publishDate 2021
url http://repositorio.unne.edu.ar/handle/123456789/28837
work_keys_str_mv AT dellacassaeduardosantiago antivenomactivityofmedicinalplantsfromsouthamerica
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AT ricciardigabrielaanaleticia antivenomactivityofmedicinalplantsfromsouthamerica
AT camargofranciscojose antivenomactivityofmedicinalplantsfromsouthamerica
AT tressenssaragraciela antivenomactivityofmedicinalplantsfromsouthamerica
AT ricciardiarmandoitaloamadeo antivenomactivityofmedicinalplantsfromsouthamerica
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