Medical cannabis in dentistry: an analysis of the clinical evidence
The objective of this study was to synthesize available scientific evidence regarding the clinical applications of cannabis as a therapeutic agent in dentistry. A narrative review was conducted based on scientific literature available in PubMed, Scielo, and Google Scholar databases through an electr...
Guardado en:
| Autores principales: | , |
|---|---|
| Formato: | Artículo revista |
| Lenguaje: | Español |
| Publicado: |
Facultad de Odontología de la Universidad Nacional del Nordeste (FOUNNE)
2025
|
| Materias: | |
| Acceso en línea: | https://revistas.unne.edu.ar/index.php/rfo/article/view/9031 |
| Aporte de: |
| id |
I48-R154-article-9031 |
|---|---|
| record_format |
ojs |
| institution |
Universidad Nacional del Nordeste |
| institution_str |
I-48 |
| repository_str |
R-154 |
| container_title_str |
Revistas UNNE - Universidad Nacional del Noroeste (UNNE) |
| language |
Español |
| format |
Artículo revista |
| topic |
cannabis sativa cannabidiol oral health topical administration cannabis sativa cannabidiol salud bucal administración tópica cannabis sativa canabidiol saúde bucal administração tópica |
| spellingShingle |
cannabis sativa cannabidiol oral health topical administration cannabis sativa cannabidiol salud bucal administración tópica cannabis sativa canabidiol saúde bucal administração tópica Mederos, Matías Francia, Alejandro Medical cannabis in dentistry: an analysis of the clinical evidence |
| topic_facet |
cannabis sativa cannabidiol oral health topical administration cannabis sativa cannabidiol salud bucal administración tópica cannabis sativa canabidiol saúde bucal administração tópica |
| author |
Mederos, Matías Francia, Alejandro |
| author_facet |
Mederos, Matías Francia, Alejandro |
| author_sort |
Mederos, Matías |
| title |
Medical cannabis in dentistry: an analysis of the clinical evidence |
| title_short |
Medical cannabis in dentistry: an analysis of the clinical evidence |
| title_full |
Medical cannabis in dentistry: an analysis of the clinical evidence |
| title_fullStr |
Medical cannabis in dentistry: an analysis of the clinical evidence |
| title_full_unstemmed |
Medical cannabis in dentistry: an analysis of the clinical evidence |
| title_sort |
medical cannabis in dentistry: an analysis of the clinical evidence |
| description |
The objective of this study was to synthesize available scientific evidence regarding the clinical applications of cannabis as a therapeutic agent in dentistry. A narrative review was conducted based on scientific literature available in PubMed, Scielo, and Google Scholar databases through an electronic search using the keywords cannabis, cannabidiol, dentistry, therapeutics, oral health, and tooth, including articles up to January 2025. The initial search yielded 438 records; after removing duplicates and reading full-text articles, 12 records were included for subsequent qualitative analysis. The oral cavity and orofacial conditions in which cannabinoids have been used as treatment are heterogeneous. The products employed are also varied; diverse extracts, both commercial and experimental, have been tested with different cannabinoids as active ingredients. Cannabinoids were administered systemically through oral ingestion in the form of oils/extracts and locally through topical application on facial skin and oral mucosa in the form of creams, gels, or toothpastes. Although clinical studies on the use of cannabinoids in different orofacial conditions have been reported, the available clinical evidence remains limited, and studies across different conditions are heterogeneous regarding treatment protocols employed as well as control methods. |
| publisher |
Facultad de Odontología de la Universidad Nacional del Nordeste (FOUNNE) |
| publishDate |
2025 |
| url |
https://revistas.unne.edu.ar/index.php/rfo/article/view/9031 |
| work_keys_str_mv |
AT mederosmatias medicalcannabisindentistryananalysisoftheclinicalevidence AT franciaalejandro medicalcannabisindentistryananalysisoftheclinicalevidence AT mederosmatias cannabismedicinalenodontologiaunanalisisdelaevidenciaclinica AT franciaalejandro cannabismedicinalenodontologiaunanalisisdelaevidenciaclinica AT mederosmatias cannabismedicinalnaodontologiaumaanalisedaevidenciaclinica AT franciaalejandro cannabismedicinalnaodontologiaumaanalisedaevidenciaclinica |
| first_indexed |
2026-01-17T05:00:59Z |
| last_indexed |
2026-01-17T05:00:59Z |
| _version_ |
1854538839363682304 |
| spelling |
I48-R154-article-90312025-12-29T12:20:53Z Medical cannabis in dentistry: an analysis of the clinical evidence Cannabis medicinal en odontología: un análisis de la evidencia clínica Cannabis medicinal na odontologia: uma análise da evidência clínica Mederos, Matías Francia, Alejandro cannabis sativa cannabidiol oral health topical administration cannabis sativa cannabidiol salud bucal administración tópica cannabis sativa canabidiol saúde bucal administração tópica The objective of this study was to synthesize available scientific evidence regarding the clinical applications of cannabis as a therapeutic agent in dentistry. A narrative review was conducted based on scientific literature available in PubMed, Scielo, and Google Scholar databases through an electronic search using the keywords cannabis, cannabidiol, dentistry, therapeutics, oral health, and tooth, including articles up to January 2025. The initial search yielded 438 records; after removing duplicates and reading full-text articles, 12 records were included for subsequent qualitative analysis. The oral cavity and orofacial conditions in which cannabinoids have been used as treatment are heterogeneous. The products employed are also varied; diverse extracts, both commercial and experimental, have been tested with different cannabinoids as active ingredients. Cannabinoids were administered systemically through oral ingestion in the form of oils/extracts and locally through topical application on facial skin and oral mucosa in the form of creams, gels, or toothpastes. Although clinical studies on the use of cannabinoids in different orofacial conditions have been reported, the available clinical evidence remains limited, and studies across different conditions are heterogeneous regarding treatment protocols employed as well as control methods. El objetivo del presente trabajo fue sintetizar la evidencia científica disponible acerca de las aplicaciones clínicas del cannabis como terapéutica en odontología. Se realizó una revisión narrativa en base a la literatura científica disponible en las bases de datos PubMed, Scielo y Google Scholar mediante una búsqueda electrónica empleando las palabras clave cannabis, cannabidiol, dentistry, therapeutics, oral health, tooth, incluyendo artículos hasta enero de 2025. En la búsqueda inicial se obtuvieron 438 registros, tras eliminar duplicados y leer artículos a texto completo, se incluyeron 12 registros para su posterior análisis cualitativo. Las condiciones de la cavidad bucal y el territorio orofacial en las que se han empleado cannabinoides como tratamiento son heterogéneas. Los productos empleados también son variados, se han testeado diversos extractos, tanto comerciales como experimentales con diferentes cannabinoides como principio activo. Los cannabinoides fueron empleados sistémicamente mediante la ingestión oral en forma de aceites/extractos y localmente mediante su aplicación tópica sobre piel en la región facial y en mucosa oral en forma de cremas, geles o pastas dentales. Si bien se han reportado estudios clínicos sobre el uso de cannabinoides en diferentes condiciones de la región orofacial, la evidencia clínica disponible aún es escasa y los estudios en las diferentes condiciones son heterogéneos en cuanto a los protocolos de tratamiento empleados así como los métodos de control. O objetivo deste trabalho foi sintetizar a evidência científica disponível sobre as aplicações clínicas da cannabis como terapêutica em odontologia. Realizou-se uma revisão narrativa baseada na literatura científica disponível nas bases de dados PubMed, Scielo e Google Scholar, mediante busca eletrônica utilizando as palavras-chave cannabis, cannabidiol, dentistry, therapeutics, oral health, tooth, incluindo artigos publicados até janeiro de 2025. Na busca inicial foram obtidos 438 registros; após a remoção de duplicatas e leitura dos textos completos, 12 estudos foram incluídos para análise qualitativa. As condições da cavidade bucal e da região orofacial nas quais canabinoides foram utilizados como tratamento são heterogêneas. Os produtos empregados também foram variados, sendo testados diferentes extratos, tanto comerciais quanto experimentais, com diversos canabinoides como princípio ativo. Os canabinoides foram administrados sistemicamente por ingestão oral em forma de óleos/extratos, e localmente por aplicação tópica sobre a pele da região facial e na mucosa oral, em forma de cremes, géis ou pastas dentais. Embora existam estudos clínicos relatando o uso de canabinoides em diferentes condições orofaciais, a evidência clínica disponível ainda é escasa, e os estudos apresentam heterogeneidade quanto aos protocolos terapêuticos e métodos de controle empregados. Facultad de Odontología de la Universidad Nacional del Nordeste (FOUNNE) 2025-12-29 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unne.edu.ar/index.php/rfo/article/view/9031 10.30972/rfo.1829031 Revista de la Facultad de Odontología; Vol. 18 Núm. 2 (2025) 2683-7986 1668-7280 spa https://revistas.unne.edu.ar/index.php/rfo/article/view/9031/8766 https://creativecommons.org/licenses/by-nc/4.0 |