Whole seeds of Bauhinia variegata L. (Fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes
Whole seeds of Bauhinia variegata L. (Fabaceae) were utilized as a biological reducer to transform benzaldehyde into benzyl alcohol. The effects of some variables such as temperature, the load of substrate and co-solvent, were established to optimize the reductive process. Utilizing the optimal reac...
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Autores principales: | , , , , , , |
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Formato: | Artículo |
Lenguaje: | Español |
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Taylor and Francis Ltd.
2021
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Acceso en línea: | http://pa.bibdigital.ucc.edu.ar/3320/1/A_Demmel_Bordon_Vazquez.pdf |
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I38-R144-3320 |
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institution |
Universidad Católica de Córdoba |
institution_str |
I-38 |
repository_str |
R-144 |
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Producción Académica Universidad Católica de Córdoba (UCCor) |
language |
Español |
orig_language_str_mv |
spa |
topic |
QD Química |
spellingShingle |
QD Química Demmel, Gabriela Inés Bordón, Daniela L. Vázquez, Ana María Decarlini, María Florencia Díaz Panero, Mariángeles Rossi, Laura I. Aimar, Mario Leandro Whole seeds of Bauhinia variegata L. (Fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes |
topic_facet |
QD Química |
description |
Whole seeds of Bauhinia variegata L. (Fabaceae) were utilized as a biological reducer to transform benzaldehyde into benzyl alcohol. The effects of some variables such as temperature, the load of substrate and co-solvent, were established to optimize the reductive process. Utilizing the optimal reaction conditions, a laboratory-scale reaction (final concentration of the substrate: 21.2 mM) was performed to obtain benzyl alcohol (conversion: 95%; isolated yield: 49%; productivity: 1.11 g L−1 or 0.046 g L−1h−1 of benzyl alcohol). In addition, using these optimal conditions, fourteen substituted benzaldehydes were reduced, with a conversion achieved to their corresponding benzyl alcohols ranging from 62% to >99% (isolated yields from 7% to 70%). Moreover, useful building blocks by the synthesis of the drugs and important commercial products were also obtained. The scope, limitations and advantages of this new biocatalytic synthetic method are also discussed. |
format |
Artículo Artículo |
author |
Demmel, Gabriela Inés Bordón, Daniela L. Vázquez, Ana María Decarlini, María Florencia Díaz Panero, Mariángeles Rossi, Laura I. Aimar, Mario Leandro |
author_facet |
Demmel, Gabriela Inés Bordón, Daniela L. Vázquez, Ana María Decarlini, María Florencia Díaz Panero, Mariángeles Rossi, Laura I. Aimar, Mario Leandro |
author_sort |
Demmel, Gabriela Inés |
title |
Whole seeds of Bauhinia variegata L. (Fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes |
title_short |
Whole seeds of Bauhinia variegata L. (Fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes |
title_full |
Whole seeds of Bauhinia variegata L. (Fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes |
title_fullStr |
Whole seeds of Bauhinia variegata L. (Fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes |
title_full_unstemmed |
Whole seeds of Bauhinia variegata L. (Fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes |
title_sort |
whole seeds of bauhinia variegata l. (fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes |
publisher |
Taylor and Francis Ltd. |
publishDate |
2021 |
url |
http://pa.bibdigital.ucc.edu.ar/3320/1/A_Demmel_Bordon_Vazquez.pdf |
work_keys_str_mv |
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bdutipo_str |
Repositorios |
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1764820535799185411 |