Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts

Rutin was isolated from dried leaves and flowers of buckwheat (Fagopyrum esculentum Moench.). The effects of rutin on angiotensin II-induced hypertrophy of cultured cardiac myocytes and proliferation of cardiac fibroblasts of neonatal rats were evaluated by analyzing the cell surface area, measuri...

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Autores principales: Han, Shu-Ying, Chu, Jin-Xiu, Li, Guang-Min, Zhu, Li-Sha, Shi, Rui-Fang
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2010
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/7883
http://www.latamjpharm.org/trabajos/29/1/LAJOP_29_1_2_5_D131M9W9AH.pdf
Aporte de:SEDICI (UNLP) de Universidad Nacional de La Plata Ver origen
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spelling I19-R120-10915-78832019-06-28T04:02:35Z http://sedici.unlp.edu.ar/handle/10915/7883 http://www.latamjpharm.org/trabajos/29/1/LAJOP_29_1_2_5_D131M9W9AH.pdf Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts Han, Shu-Ying Chu, Jin-Xiu Li, Guang-Min Zhu, Li-Sha Shi, Rui-Fang 2010 2010-02-17T03:00:00Z en Farmacia Farmacología Plantas medicinales Enfermedades cardiovasculares Rutin was isolated from dried leaves and flowers of buckwheat (Fagopyrum esculentum Moench.). The effects of rutin on angiotensin II-induced hypertrophy of cultured cardiac myocytes and proliferation of cardiac fibroblasts of neonatal rats were evaluated by analyzing the cell surface area, measuring the protein synthesis rate through 3H-leucine incorporation, and the MTT method. Rutin (0.8 to 8.0 mg/l) exhibited a strong inhibition on the hypertrophy and proliferation. The results suggested that rutin from buckwheat flowers and leaves might have protective effects on cardiac hypertrophy. Colegio de Farmacéuticos de la Provincia de Buenos Aires Articulo Comunicacion application/pdf 137-140
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Farmacología
Plantas medicinales
Enfermedades cardiovasculares
spellingShingle Farmacia
Farmacología
Plantas medicinales
Enfermedades cardiovasculares
Han, Shu-Ying
Chu, Jin-Xiu
Li, Guang-Min
Zhu, Li-Sha
Shi, Rui-Fang
Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
topic_facet Farmacia
Farmacología
Plantas medicinales
Enfermedades cardiovasculares
description Rutin was isolated from dried leaves and flowers of buckwheat (Fagopyrum esculentum Moench.). The effects of rutin on angiotensin II-induced hypertrophy of cultured cardiac myocytes and proliferation of cardiac fibroblasts of neonatal rats were evaluated by analyzing the cell surface area, measuring the protein synthesis rate through 3H-leucine incorporation, and the MTT method. Rutin (0.8 to 8.0 mg/l) exhibited a strong inhibition on the hypertrophy and proliferation. The results suggested that rutin from buckwheat flowers and leaves might have protective effects on cardiac hypertrophy.
format Articulo
Comunicacion
author Han, Shu-Ying
Chu, Jin-Xiu
Li, Guang-Min
Zhu, Li-Sha
Shi, Rui-Fang
author_facet Han, Shu-Ying
Chu, Jin-Xiu
Li, Guang-Min
Zhu, Li-Sha
Shi, Rui-Fang
author_sort Han, Shu-Ying
title Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
title_short Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
title_full Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
title_fullStr Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
title_full_unstemmed Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
title_sort effects of rutin from leaves and flowers of buckwheat (fagopyrum esculentum moench.) on angiotensin ii-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/7883
http://www.latamjpharm.org/trabajos/29/1/LAJOP_29_1_2_5_D131M9W9AH.pdf
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