Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts

Rutin was isolated from dried leaves and flowers of buckwheat (Fagopyrum esculentum Moench.). The effects of rutin on angiotensin II-induced hypertrophy of cultured cardiac myocytes and proliferation of cardiac fibroblasts of neonatal rats were evaluated by analyzing the cell surface area, measuri...

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Autores principales: Han, Shu-Ying, Chu, Jin-Xiu, Li, Guang-Min, Zhu, Li-Sha, Shi, Rui-Fang
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2010
Materias:
Farmacia
Farmacología
Plantas medicinales
Enfermedades cardiovasculares
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/7883
http://www.latamjpharm.org/trabajos/29/1/LAJOP_29_1_2_5_D131M9W9AH.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-7883
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Farmacología
Plantas medicinales
Enfermedades cardiovasculares
spellingShingle Farmacia
Farmacología
Plantas medicinales
Enfermedades cardiovasculares
Han, Shu-Ying
Chu, Jin-Xiu
Li, Guang-Min
Zhu, Li-Sha
Shi, Rui-Fang
Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
topic_facet Farmacia
Farmacología
Plantas medicinales
Enfermedades cardiovasculares
description Rutin was isolated from dried leaves and flowers of buckwheat (Fagopyrum esculentum Moench.). The effects of rutin on angiotensin II-induced hypertrophy of cultured cardiac myocytes and proliferation of cardiac fibroblasts of neonatal rats were evaluated by analyzing the cell surface area, measuring the protein synthesis rate through 3H-leucine incorporation, and the MTT method. Rutin (0.8 to 8.0 mg/l) exhibited a strong inhibition on the hypertrophy and proliferation. The results suggested that rutin from buckwheat flowers and leaves might have protective effects on cardiac hypertrophy.
format Articulo
Comunicacion
author Han, Shu-Ying
Chu, Jin-Xiu
Li, Guang-Min
Zhu, Li-Sha
Shi, Rui-Fang
author_facet Han, Shu-Ying
Chu, Jin-Xiu
Li, Guang-Min
Zhu, Li-Sha
Shi, Rui-Fang
author_sort Han, Shu-Ying
title Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
title_short Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
title_full Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
title_fullStr Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
title_full_unstemmed Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
title_sort effects of rutin from leaves and flowers of buckwheat (fagopyrum esculentum moench.) on angiotensin ii-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/7883
http://www.latamjpharm.org/trabajos/29/1/LAJOP_29_1_2_5_D131M9W9AH.pdf
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