Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts
Rutin was isolated from dried leaves and flowers of buckwheat (Fagopyrum esculentum Moench.). The effects of rutin on angiotensin II-induced hypertrophy of cultured cardiac myocytes and proliferation of cardiac fibroblasts of neonatal rats were evaluated by analyzing the cell surface area, measuri...
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Autores principales: | , , , , |
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Formato: | Articulo Comunicacion |
Lenguaje: | Inglés |
Publicado: |
2010
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Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/7883 http://www.latamjpharm.org/trabajos/29/1/LAJOP_29_1_2_5_D131M9W9AH.pdf |
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I19-R120-10915-7883 |
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record_format |
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institution |
Universidad Nacional de La Plata |
institution_str |
I-19 |
repository_str |
R-120 |
collection |
SEDICI (UNLP) |
language |
Inglés |
topic |
Farmacia Farmacología Plantas medicinales Enfermedades cardiovasculares |
spellingShingle |
Farmacia Farmacología Plantas medicinales Enfermedades cardiovasculares Han, Shu-Ying Chu, Jin-Xiu Li, Guang-Min Zhu, Li-Sha Shi, Rui-Fang Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts |
topic_facet |
Farmacia Farmacología Plantas medicinales Enfermedades cardiovasculares |
description |
Rutin was isolated from dried leaves and flowers of buckwheat (Fagopyrum esculentum
Moench.). The effects of rutin on angiotensin II-induced hypertrophy of cultured cardiac myocytes and
proliferation of cardiac fibroblasts of neonatal rats were evaluated by analyzing the cell surface area, measuring
the protein synthesis rate through 3H-leucine incorporation, and the MTT method. Rutin (0.8 to 8.0
mg/l) exhibited a strong inhibition on the hypertrophy and proliferation. The results suggested that rutin
from buckwheat flowers and leaves might have protective effects on cardiac hypertrophy. |
format |
Articulo Comunicacion |
author |
Han, Shu-Ying Chu, Jin-Xiu Li, Guang-Min Zhu, Li-Sha Shi, Rui-Fang |
author_facet |
Han, Shu-Ying Chu, Jin-Xiu Li, Guang-Min Zhu, Li-Sha Shi, Rui-Fang |
author_sort |
Han, Shu-Ying |
title |
Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts |
title_short |
Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts |
title_full |
Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts |
title_fullStr |
Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts |
title_full_unstemmed |
Effects of rutin from leaves and flowers of buckwheat (Fagopyrum esculentum Moench.) on angiotensin II-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts |
title_sort |
effects of rutin from leaves and flowers of buckwheat (fagopyrum esculentum moench.) on angiotensin ii-induced hypertrophy of cardiac myocytes and proliferation of fibroblasts |
publishDate |
2010 |
url |
http://sedici.unlp.edu.ar/handle/10915/7883 http://www.latamjpharm.org/trabajos/29/1/LAJOP_29_1_2_5_D131M9W9AH.pdf |
work_keys_str_mv |
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Repositorios |
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