Conjugated linoleic acid and fatty acid binding protein as antioxidants

Studies were carried out to determine the effect of conjugated linoleic acid (CLA) and rat liver cytosolic protein enriched in fatty acid binding protein (FABP) on the non-enzymatic lipid peroxidation of rat liver microsomes. The inhibition of lipid peroxidation was more evident when the FABP contai...

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Autores principales: Piergiacomi, Viviana Angélica, Palacios, Alejandro
Formato: Articulo
Lenguaje:Inglés
Publicado: 2006
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/107536
http://www.fvet.uba.ar/fcvanterior/publicaciones/archivos/Volumen8N1/piergiacomi8.pdf
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id I19-R120-10915-107536
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Conjugated linoleic acid
Fatty acid binding protein
Lipid peroxidation
Liver
Microsomes
spellingShingle Ciencias Veterinarias
Conjugated linoleic acid
Fatty acid binding protein
Lipid peroxidation
Liver
Microsomes
Piergiacomi, Viviana Angélica
Palacios, Alejandro
Conjugated linoleic acid and fatty acid binding protein as antioxidants
topic_facet Ciencias Veterinarias
Conjugated linoleic acid
Fatty acid binding protein
Lipid peroxidation
Liver
Microsomes
description Studies were carried out to determine the effect of conjugated linoleic acid (CLA) and rat liver cytosolic protein enriched in fatty acid binding protein (FABP) on the non-enzymatic lipid peroxidation of rat liver microsomes. The inhibition of lipid peroxidation was more evident when the FABP containing fraction obtained from CLA-group was used with either kind of microsomes (CLA and control). The chemiluminescence and polyunsaturated fatty acid composition of rat liver microsomes changed after CLA treatment. When native and peroxidized microsomes obtained from control group were compared, the most affected polyunsaturated fatty acids were: C18:2, C18:3 and C20:4, while in CLA-group C20:4 was mainly peroxidized The simultaneous analysis of chemiluminescence and fatty acid composition demonstrated that CLA and FABP play a role protecting rat liver microsomes against the harmful effect of lipid peroxidation.
format Articulo
Articulo
author Piergiacomi, Viviana Angélica
Palacios, Alejandro
author_facet Piergiacomi, Viviana Angélica
Palacios, Alejandro
author_sort Piergiacomi, Viviana Angélica
title Conjugated linoleic acid and fatty acid binding protein as antioxidants
title_short Conjugated linoleic acid and fatty acid binding protein as antioxidants
title_full Conjugated linoleic acid and fatty acid binding protein as antioxidants
title_fullStr Conjugated linoleic acid and fatty acid binding protein as antioxidants
title_full_unstemmed Conjugated linoleic acid and fatty acid binding protein as antioxidants
title_sort conjugated linoleic acid and fatty acid binding protein as antioxidants
publishDate 2006
url http://sedici.unlp.edu.ar/handle/10915/107536
http://www.fvet.uba.ar/fcvanterior/publicaciones/archivos/Volumen8N1/piergiacomi8.pdf
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