Overcoming the hurdles of tumor immunity by targeting regulatory pathways in innate and adaptive immune cells

por Zwirner, N.W., Croci, D.O., Domaica, C.I., Rabinovich, G.A.

Human Natural Killer Cell Maturation Defect Supports In Vivo CD56bright to CD56dim Lineage Development

por Domaica, C.I., Fuertes, M.B., Uriarte, I., Girart, M.V., Sardañons, J., Comas, D.I., Di Giovanni, D., Gaillard, M.I., Bezrodnik, L., Zwirner, N.W.
Publicado 2012

Human Natural Killer Cell Maturation Defect Supports In Vivo CD56bright to CD56dim Lineage Development

por Domaica, C.I., Fuertes, M.B., Uriarte, I., Girart, M.V., Sardañons, J., Comas, D.I., Di Giovanni, D., Gaillard, M.I., Bezrodnik, L., Zwirner, N.W.

IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness

por Ziblat, A., Domaica, C.I., Spallanzani, R.G., Iraolagoitia, X.L.R., Rossi, L.E., Avila, D.E., Torres, N.I., Fuertes, M.B., Zwirner, N.W.

Human Natural Killer Cell Maturation Defect Supports In Vivo CD56bright to CD56dim Lineage Development

por Domaica, C.I., Fuertes, M.B., Uriarte, I., Girart, M.V., Sardañons, J., Comas, D.I., Di Giovanni, D., Gaillard, M.I., Bezrodnik, L., Zwirner, N.W.
Publicado 2012

Human M2 macrophages limit NK cell effector functions through secretion of TGF-b and engagement of CD85j

por Nuñez, S.Y., Ziblat, A., Secchiari, F., Torres, N.I., Sierra, J.M., Raffo Iraolagoitia, X.L., Araya, R.E., Domaica, C.I., Fuertes, M.B., Zwirner, N.W.

Interleukin (IL)-23 stimulates IFN-γ secretion by CD56bright natural killer cells and enhances IL-18-driven dendritic cells activation

por Ziblat, A., Nuñez, S.Y., Iraolagoitia, X.L.R., Spallanzani, R.G., Torres, N.I., Sierra, J.M., Secchiari, F., Domaica, C.I., Fuertes, M.B., Zwirner, N.W.

Regulatory dendritic cells restrain NK cell IFN-γ production through mechanisms involving NKp46, IL-10, and MHC class I-specific inhibitory receptors

por Spallanzani, R.G., Torres, N.I., Avila, D.E., Ziblat, A., Raffo Iraolagoitia, X.L., Rossi, L.E., Domaica, C.I., Fuertes, M.B., Rabinovich, G.A., Zwirner, N.W.

Expansion of CD11b+Ly6G+Ly6Cint cells driven by medroxyprogesterone acetate in mice bearing breast tumors restrains NK cell effector functions

por Spallanzani, R.G., Dalotto-Moreno, T., Raffo Iraolagoitia, X.L., Ziblat, A., Domaica, C.I., Avila, D.E., Rossi, L.E., Fuertes, M.B., Battistone, M.A., Rabinovich, G.A., Salatino, M., Zwirner, N.W.

NK cells restrain spontaneous antitumor CD8+ T cell priming through pd-1/pd-l1 interactions with dendritic cells

por Raffo Iraolagoitia, X.L., Spallanzani, R.G., Torres, N.I., Araya, R.E., Ziblat, A., Domaica, C.I., Sierra, J.M., Nuñez, S.Y., Secchiari, F., Gajewski, T.F., Zwirner, N.W., Fuertes, M.B.

Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma

por Croci, D.O., Salatino, M., Rubinstein, N., Cerliani, J.P., Cavallin, L.E., Leung, H.J., Ouyang, J., Ilarregui, J.M., Toscano, M.A., Domaica, C.I., Croci, M.C., Shipp, M.A., Mesri, E.A., Albini, A., Rabinovich, G.A.
Publicado 2012

Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma

por Croci, D.O., Salatino, M., Rubinstein, N., Cerliani, J.P., Cavallin, L.E., Leung, H.J., Ouyang, J., Ilarregui, J.M., Toscano, M.A., Domaica, C.I., Croci, M.C., Shipp, M.A., Mesri, E.A., Albini, A., Rabinovich, G.A.

Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma

por Croci, D.O., Salatino, M., Rubinstein, N., Cerliani, J.P., Cavallin, L.E., Leung, H.J., Ouyang, J., Ilarregui, J.M., Toscano, M.A., Domaica, C.I., Croci, M.C., Shipp, M.A., Mesri, E.A., Albini, A., Rabinovich, G.A.
Publicado 2012