Animals Article animal 416 nonhuman 406 controlled study 332 metabolism 260 priority journal 242 animal experiment 216 male 180 animal cell 164 drug effects 164 animal tissue 162 female 158 physiology 156 Male 150 mouse 150 unclassified drug 124 Mice 122 Female 118 genetics 118 human 112 Humans 110 adult 98 protein expression 88 chemistry 78 animal model 72 in vitro study 60 enzyme activity 54 signal transduction 54 pathology 52