article nonhuman 266 controlled study 200 priority journal 190 Animals 152 unclassified drug 134 cytokine production 94 human 94 Humans 86 animal cell 78 female 78 metabolism 68 mouse 68 Female 66 Mice 66 animal experiment 60 human cell 58 protein expression 58 animal 54 Argentina 52 chemistry 48 gamma interferon 44 enzyme activity 42 Animalia 38 drug effect 38 in vitro study 38 male 38 physiology 38 immune response 36 gene expression 34