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article 126 nonhuman 73 controlled study 60 Male 59 Mice 55 male 55 mouse 55 Porphyrins 53 priority journal 51 porphyrin 50 Animals 47 Support, Non-U.S. Gov't 46 metabolism 45 animal experiment 44 human 40 Aminolevulinic Acid 39 Liver 37 aminolevulinic acid 37 animal tissue 35 5 aminolevulinate synthase 32 porphobilinogen synthase 31 Animal 30 Kinetics 30 enzyme activity 29 5-Aminolevulinate Synthetase 28 Heme 28 Porphobilinogen Synthase 28 heme 27 animal model 26 enzymology 26