animal experiment metabolism animal 389 nonhuman 386 controlled study 363 Animals 359 priority journal 239 Article 236 mouse 223 animal tissue 218 male 193 Mice 185 article 182 female 182 Male 165 animal cell 163 animal model 163 physiology 155 Female 154 unclassified drug 138 drug effects 118 protein expression 118 genetics 117 rat 106 human 100 drug effect 94 pathology 94 Humans 93 in vitro study 91 Rats 88