animal experiment nonhuman 364 controlled study 322 Animals 303 priority journal 287 article 280 animal tissue 215 mouse 206 Mice 177 protein expression 175 animal model 173 female 157 animal cell 156 male 155 Female 153 Male 130 rat 108 Rats 102 unclassified drug 100 animal 94 Humans 90 metabolism 87 down regulation 84 gene expression regulation 83 human 82 Article 76 gene expression 76 Gene Expression Regulation 74 cell proliferation 74 messenger RNA 70