Effect on rats and mice of a diet with low tryptophan content (maize flour)
Female Wistar rats when crowded together become aggressive if fed a diet with low tryptophan (Trp) content (maize flour, Mf). When isolated during 30 days and fed Mf, they show a decrease of weight, of total plasma Trp, and of Trp and 5-hydroxytryptamine (5-HT) in brain stem, but 5-hydroxyindolaceti...
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todo:paper_NIS18561_v29_n4-5_p239_Izquierdo2023-10-03T16:46:05Z Effect on rats and mice of a diet with low tryptophan content (maize flour) Izquierdo, J.A. Rabiller, G. Maris Costas, S. Justel, E.A. Savini, C.V. 5 hydroxyindoleacetic acid brain monoamine serotonin tryptophan aggression animal experiment brain stem central nervous system diet drug blood level mouse oral drug administration Aggression Animals Body Weight Brain Stem Diet Female Flour Humans Hydroxyindoleacetic Acid Male Mice Rats Rats, Inbred Strains Serotonin Tryptophan Tryptophan Oxygenase Zea mays Female Wistar rats when crowded together become aggressive if fed a diet with low tryptophan (Trp) content (maize flour, Mf). When isolated during 30 days and fed Mf, they show a decrease of weight, of total plasma Trp, and of Trp and 5-hydroxytryptamine (5-HT) in brain stem, but 5-hydroxyindolacetic acid (5-HIAA) of the same cerebral area does not change. These results partially agree with other authors' observations. Mice isolated during 47 days and fed with Mf do not show any significant weight variation, the hypermotility of isolated mice on normal diet persists, but 5-HT and 5-HIAA significantly decrease in total brain, an effect that has been observed by another author. The effect of 5-HIAA does not depend on the diet, either balanced or with low Trp content. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_NIS18561_v29_n4-5_p239_Izquierdo |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
5 hydroxyindoleacetic acid brain monoamine serotonin tryptophan aggression animal experiment brain stem central nervous system diet drug blood level mouse oral drug administration Aggression Animals Body Weight Brain Stem Diet Female Flour Humans Hydroxyindoleacetic Acid Male Mice Rats Rats, Inbred Strains Serotonin Tryptophan Tryptophan Oxygenase Zea mays |
spellingShingle |
5 hydroxyindoleacetic acid brain monoamine serotonin tryptophan aggression animal experiment brain stem central nervous system diet drug blood level mouse oral drug administration Aggression Animals Body Weight Brain Stem Diet Female Flour Humans Hydroxyindoleacetic Acid Male Mice Rats Rats, Inbred Strains Serotonin Tryptophan Tryptophan Oxygenase Zea mays Izquierdo, J.A. Rabiller, G. Maris Costas, S. Justel, E.A. Savini, C.V. Effect on rats and mice of a diet with low tryptophan content (maize flour) |
topic_facet |
5 hydroxyindoleacetic acid brain monoamine serotonin tryptophan aggression animal experiment brain stem central nervous system diet drug blood level mouse oral drug administration Aggression Animals Body Weight Brain Stem Diet Female Flour Humans Hydroxyindoleacetic Acid Male Mice Rats Rats, Inbred Strains Serotonin Tryptophan Tryptophan Oxygenase Zea mays |
description |
Female Wistar rats when crowded together become aggressive if fed a diet with low tryptophan (Trp) content (maize flour, Mf). When isolated during 30 days and fed Mf, they show a decrease of weight, of total plasma Trp, and of Trp and 5-hydroxytryptamine (5-HT) in brain stem, but 5-hydroxyindolacetic acid (5-HIAA) of the same cerebral area does not change. These results partially agree with other authors' observations. Mice isolated during 47 days and fed with Mf do not show any significant weight variation, the hypermotility of isolated mice on normal diet persists, but 5-HT and 5-HIAA significantly decrease in total brain, an effect that has been observed by another author. The effect of 5-HIAA does not depend on the diet, either balanced or with low Trp content. |
format |
JOUR |
author |
Izquierdo, J.A. Rabiller, G. Maris Costas, S. Justel, E.A. Savini, C.V. |
author_facet |
Izquierdo, J.A. Rabiller, G. Maris Costas, S. Justel, E.A. Savini, C.V. |
author_sort |
Izquierdo, J.A. |
title |
Effect on rats and mice of a diet with low tryptophan content (maize flour) |
title_short |
Effect on rats and mice of a diet with low tryptophan content (maize flour) |
title_full |
Effect on rats and mice of a diet with low tryptophan content (maize flour) |
title_fullStr |
Effect on rats and mice of a diet with low tryptophan content (maize flour) |
title_full_unstemmed |
Effect on rats and mice of a diet with low tryptophan content (maize flour) |
title_sort |
effect on rats and mice of a diet with low tryptophan content (maize flour) |
url |
http://hdl.handle.net/20.500.12110/paper_NIS18561_v29_n4-5_p239_Izquierdo |
work_keys_str_mv |
AT izquierdoja effectonratsandmiceofadietwithlowtryptophancontentmaizeflour AT rabillerg effectonratsandmiceofadietwithlowtryptophancontentmaizeflour AT mariscostass effectonratsandmiceofadietwithlowtryptophancontentmaizeflour AT justelea effectonratsandmiceofadietwithlowtryptophancontentmaizeflour AT savinicv effectonratsandmiceofadietwithlowtryptophancontentmaizeflour |
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