Effect on rats and mice of a diet with low tryptophan content (maize flour)

Female Wistar rats when crowded together become aggressive if fed a diet with low tryptophan (Trp) content (maize flour, Mf). When isolated during 30 days and fed Mf, they show a decrease of weight, of total plasma Trp, and of Trp and 5-hydroxytryptamine (5-HT) in brain stem, but 5-hydroxyindolaceti...

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Autores principales: Izquierdo, J.A., Rabiller, G., Maris Costas, S., Justel, E.A., Savini, C.V.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_NIS18561_v29_n4-5_p239_Izquierdo
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spelling todo:paper_NIS18561_v29_n4-5_p239_Izquierdo2023-10-03T16:46:05Z Effect on rats and mice of a diet with low tryptophan content (maize flour) Izquierdo, J.A. Rabiller, G. Maris Costas, S. Justel, E.A. Savini, C.V. 5 hydroxyindoleacetic acid brain monoamine serotonin tryptophan aggression animal experiment brain stem central nervous system diet drug blood level mouse oral drug administration Aggression Animals Body Weight Brain Stem Diet Female Flour Humans Hydroxyindoleacetic Acid Male Mice Rats Rats, Inbred Strains Serotonin Tryptophan Tryptophan Oxygenase Zea mays Female Wistar rats when crowded together become aggressive if fed a diet with low tryptophan (Trp) content (maize flour, Mf). When isolated during 30 days and fed Mf, they show a decrease of weight, of total plasma Trp, and of Trp and 5-hydroxytryptamine (5-HT) in brain stem, but 5-hydroxyindolacetic acid (5-HIAA) of the same cerebral area does not change. These results partially agree with other authors' observations. Mice isolated during 47 days and fed with Mf do not show any significant weight variation, the hypermotility of isolated mice on normal diet persists, but 5-HT and 5-HIAA significantly decrease in total brain, an effect that has been observed by another author. The effect of 5-HIAA does not depend on the diet, either balanced or with low Trp content. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_NIS18561_v29_n4-5_p239_Izquierdo
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic 5 hydroxyindoleacetic acid
brain monoamine
serotonin
tryptophan
aggression
animal experiment
brain stem
central nervous system
diet
drug blood level
mouse
oral drug administration
Aggression
Animals
Body Weight
Brain Stem
Diet
Female
Flour
Humans
Hydroxyindoleacetic Acid
Male
Mice
Rats
Rats, Inbred Strains
Serotonin
Tryptophan
Tryptophan Oxygenase
Zea mays
spellingShingle 5 hydroxyindoleacetic acid
brain monoamine
serotonin
tryptophan
aggression
animal experiment
brain stem
central nervous system
diet
drug blood level
mouse
oral drug administration
Aggression
Animals
Body Weight
Brain Stem
Diet
Female
Flour
Humans
Hydroxyindoleacetic Acid
Male
Mice
Rats
Rats, Inbred Strains
Serotonin
Tryptophan
Tryptophan Oxygenase
Zea mays
Izquierdo, J.A.
Rabiller, G.
Maris Costas, S.
Justel, E.A.
Savini, C.V.
Effect on rats and mice of a diet with low tryptophan content (maize flour)
topic_facet 5 hydroxyindoleacetic acid
brain monoamine
serotonin
tryptophan
aggression
animal experiment
brain stem
central nervous system
diet
drug blood level
mouse
oral drug administration
Aggression
Animals
Body Weight
Brain Stem
Diet
Female
Flour
Humans
Hydroxyindoleacetic Acid
Male
Mice
Rats
Rats, Inbred Strains
Serotonin
Tryptophan
Tryptophan Oxygenase
Zea mays
description Female Wistar rats when crowded together become aggressive if fed a diet with low tryptophan (Trp) content (maize flour, Mf). When isolated during 30 days and fed Mf, they show a decrease of weight, of total plasma Trp, and of Trp and 5-hydroxytryptamine (5-HT) in brain stem, but 5-hydroxyindolacetic acid (5-HIAA) of the same cerebral area does not change. These results partially agree with other authors' observations. Mice isolated during 47 days and fed with Mf do not show any significant weight variation, the hypermotility of isolated mice on normal diet persists, but 5-HT and 5-HIAA significantly decrease in total brain, an effect that has been observed by another author. The effect of 5-HIAA does not depend on the diet, either balanced or with low Trp content.
format JOUR
author Izquierdo, J.A.
Rabiller, G.
Maris Costas, S.
Justel, E.A.
Savini, C.V.
author_facet Izquierdo, J.A.
Rabiller, G.
Maris Costas, S.
Justel, E.A.
Savini, C.V.
author_sort Izquierdo, J.A.
title Effect on rats and mice of a diet with low tryptophan content (maize flour)
title_short Effect on rats and mice of a diet with low tryptophan content (maize flour)
title_full Effect on rats and mice of a diet with low tryptophan content (maize flour)
title_fullStr Effect on rats and mice of a diet with low tryptophan content (maize flour)
title_full_unstemmed Effect on rats and mice of a diet with low tryptophan content (maize flour)
title_sort effect on rats and mice of a diet with low tryptophan content (maize flour)
url http://hdl.handle.net/20.500.12110/paper_NIS18561_v29_n4-5_p239_Izquierdo
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