Pharmacological approaches to tinnitus treatment

Keypoints: 1.Available treatments for the management of -tinnitus are diverse. 2.Although most patients benefit from treatment to some degree a large percentage of them are left untreated and in despair with the notion that they have to learn to live with their tinnitus. 3.Currently there is no drug...

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Detalles Bibliográficos
Autores principales: Elgoyhen, A.B., Langguth, B.
Formato: CHAP
Materias:
Hearing
Lidocaine
Neramexane
Noise trauma
Phantom sound
Tinnitus
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_97816076_v_n_p625_Elgoyhen
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
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spelling todo:paper_97816076_v_n_p625_Elgoyhen2023-10-03T16:44:09Z Pharmacological approaches to tinnitus treatment Elgoyhen, A.B. Langguth, B. Hearing Lidocaine Neramexane Noise trauma Phantom sound Tinnitus Keypoints: 1.Available treatments for the management of -tinnitus are diverse. 2.Although most patients benefit from treatment to some degree a large percentage of them are left untreated and in despair with the notion that they have to learn to live with their tinnitus. 3.Currently there is no drug that is approved by the Food and Drug Administration (FDA) or the European Medicines Agency (EMEA) for the treatment of tinnitus. Thus, tinnitus is still a clinically unmet need, and most patients would welcome a drug that abolishes their phantom sound once and for all. 4.There are different forms of tinnitus which probably differ in their response to pharmacological treatment. Thus, even if a specific drug has failed to demonstrate efficacy in controlled clinical trials in a large sample, a beneficial effect in a subgroup of tinnitus patients should not be precluded. At present, most evidence-based pharmacological treatments treat specific comorbidities rather than the core of the disorder itself. 5.There is an urgent need for effective treatment approaches. Since in some individuals, tinnitus causes irritability agitation, stress, depression, insom-nia, and interferes with normal life - leading to suicidal attempts in severe cases - even a drug that produces a small but significant effect would have an enormous therapeutic impact. This review describes strategies currently available for tinnitus pharmacotherapy. © Springer Science+Business Media, LLC 2011. CHAP info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_97816076_v_n_p625_Elgoyhen
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Hearing
Lidocaine
Neramexane
Noise trauma
Phantom sound
Tinnitus
spellingShingle Hearing
Lidocaine
Neramexane
Noise trauma
Phantom sound
Tinnitus
Elgoyhen, A.B.
Langguth, B.
Pharmacological approaches to tinnitus treatment
topic_facet Hearing
Lidocaine
Neramexane
Noise trauma
Phantom sound
Tinnitus
description Keypoints: 1.Available treatments for the management of -tinnitus are diverse. 2.Although most patients benefit from treatment to some degree a large percentage of them are left untreated and in despair with the notion that they have to learn to live with their tinnitus. 3.Currently there is no drug that is approved by the Food and Drug Administration (FDA) or the European Medicines Agency (EMEA) for the treatment of tinnitus. Thus, tinnitus is still a clinically unmet need, and most patients would welcome a drug that abolishes their phantom sound once and for all. 4.There are different forms of tinnitus which probably differ in their response to pharmacological treatment. Thus, even if a specific drug has failed to demonstrate efficacy in controlled clinical trials in a large sample, a beneficial effect in a subgroup of tinnitus patients should not be precluded. At present, most evidence-based pharmacological treatments treat specific comorbidities rather than the core of the disorder itself. 5.There is an urgent need for effective treatment approaches. Since in some individuals, tinnitus causes irritability agitation, stress, depression, insom-nia, and interferes with normal life - leading to suicidal attempts in severe cases - even a drug that produces a small but significant effect would have an enormous therapeutic impact. This review describes strategies currently available for tinnitus pharmacotherapy. © Springer Science+Business Media, LLC 2011.
format CHAP
author Elgoyhen, A.B.
Langguth, B.
author_facet Elgoyhen, A.B.
Langguth, B.
author_sort Elgoyhen, A.B.
title Pharmacological approaches to tinnitus treatment
title_short Pharmacological approaches to tinnitus treatment
title_full Pharmacological approaches to tinnitus treatment
title_fullStr Pharmacological approaches to tinnitus treatment
title_full_unstemmed Pharmacological approaches to tinnitus treatment
title_sort pharmacological approaches to tinnitus treatment
url http://hdl.handle.net/20.500.12110/paper_97816076_v_n_p625_Elgoyhen
work_keys_str_mv AT elgoyhenab pharmacologicalapproachestotinnitustreatment
AT langguthb pharmacologicalapproachestotinnitustreatment
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