Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties

Polymeric materials having biomedical applications can be classified into two major groups according to their use: those employed in prosthetic devices, such as cardiovascular and orthopedic prostheses; and those employed as therapeutic systems, such as drug carriers. Among prosthetic systems, polym...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Parisi, M., Manzano, V.E., Flor, S., Lissarrague, M.H., Ribba, L., Lucangioli, S., D'Accorso, N.B., Goyanes, S.
Formato: CHAP
Materias:
Bone-tissue engineering
Cardiovascular-tissue engineering
Medical device
Specific drug administration
Biocompatibility
Biomechanics
Bone
Chemical properties
Diagnosis
Esters
Medical applications
Prosthetics
Tissue
Tissue engineering
Biomedical applications
Bone tissue engineering
Cardiovascular tissue engineering
Drug administration
Medical Devices
Orthopedic prosthesis
Physical and chemical properties
Therapeutic treatments
Functional polymers
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_97811190_v1_n_p369_Parisi
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_97811190_v1_n_p369_Parisi
record_format dspace
spelling todo:paper_97811190_v1_n_p369_Parisi2023-10-03T16:42:56Z Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties Parisi, M. Manzano, V.E. Flor, S. Lissarrague, M.H. Ribba, L. Lucangioli, S. D'Accorso, N.B. Goyanes, S. Bone-tissue engineering Cardiovascular-tissue engineering Medical device Specific drug administration Biocompatibility Biomechanics Bone Chemical properties Diagnosis Esters Medical applications Prosthetics Tissue Tissue engineering Biomedical applications Bone tissue engineering Cardiovascular tissue engineering Drug administration Medical Devices Orthopedic prosthesis Physical and chemical properties Therapeutic treatments Functional polymers Polymeric materials having biomedical applications can be classified into two major groups according to their use: those employed in prosthetic devices, such as cardiovascular and orthopedic prostheses; and those employed as therapeutic systems, such as drug carriers. Among prosthetic systems, polymeric materials can be used as coatings or as cemented prostheses. Some of the major advantages in using polymeric materials for biomedical applications are their flexibility, biocompatibility, the possibility of tailoring their mechanical properties and their ability to incorporate therapeutic agents into their matrix in order to allow drug administration at a specific site. The aim of this chapter is to summarize the uses and applications in the field of medical devices, as well as to discuss the pharmaceutical, physical and chemical properties of two of the most popular biomedical polymers: poly(methyl methacrylate) and polyurethanes (PU). In particular, we will center our attention on their use as site-specific drug administration and their application in two great areas of prosthetic devices, bone tissue and cardiovascular engineering. We will also cover their use in diagnosis and in therapeutic treatments along with advances and future perspectives in both areas. © 2015 Scrivener Publishing LLC. All rights reserved. CHAP info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_97811190_v1_n_p369_Parisi
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Bone-tissue engineering
Cardiovascular-tissue engineering
Medical device
Specific drug administration
Biocompatibility
Biomechanics
Bone
Chemical properties
Diagnosis
Esters
Medical applications
Prosthetics
Tissue
Tissue engineering
Biomedical applications
Bone tissue engineering
Cardiovascular tissue engineering
Drug administration
Medical Devices
Orthopedic prosthesis
Physical and chemical properties
Therapeutic treatments
Functional polymers
spellingShingle Bone-tissue engineering
Cardiovascular-tissue engineering
Medical device
Specific drug administration
Biocompatibility
Biomechanics
Bone
Chemical properties
Diagnosis
Esters
Medical applications
Prosthetics
Tissue
Tissue engineering
Biomedical applications
Bone tissue engineering
Cardiovascular tissue engineering
Drug administration
Medical Devices
Orthopedic prosthesis
Physical and chemical properties
Therapeutic treatments
Functional polymers
Parisi, M.
Manzano, V.E.
Flor, S.
Lissarrague, M.H.
Ribba, L.
Lucangioli, S.
D'Accorso, N.B.
Goyanes, S.
Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties
topic_facet Bone-tissue engineering
Cardiovascular-tissue engineering
Medical device
Specific drug administration
Biocompatibility
Biomechanics
Bone
Chemical properties
Diagnosis
Esters
Medical applications
Prosthetics
Tissue
Tissue engineering
Biomedical applications
Bone tissue engineering
Cardiovascular tissue engineering
Drug administration
Medical Devices
Orthopedic prosthesis
Physical and chemical properties
Therapeutic treatments
Functional polymers
description Polymeric materials having biomedical applications can be classified into two major groups according to their use: those employed in prosthetic devices, such as cardiovascular and orthopedic prostheses; and those employed as therapeutic systems, such as drug carriers. Among prosthetic systems, polymeric materials can be used as coatings or as cemented prostheses. Some of the major advantages in using polymeric materials for biomedical applications are their flexibility, biocompatibility, the possibility of tailoring their mechanical properties and their ability to incorporate therapeutic agents into their matrix in order to allow drug administration at a specific site. The aim of this chapter is to summarize the uses and applications in the field of medical devices, as well as to discuss the pharmaceutical, physical and chemical properties of two of the most popular biomedical polymers: poly(methyl methacrylate) and polyurethanes (PU). In particular, we will center our attention on their use as site-specific drug administration and their application in two great areas of prosthetic devices, bone tissue and cardiovascular engineering. We will also cover their use in diagnosis and in therapeutic treatments along with advances and future perspectives in both areas. © 2015 Scrivener Publishing LLC. All rights reserved.
format CHAP
author Parisi, M.
Manzano, V.E.
Flor, S.
Lissarrague, M.H.
Ribba, L.
Lucangioli, S.
D'Accorso, N.B.
Goyanes, S.
author_facet Parisi, M.
Manzano, V.E.
Flor, S.
Lissarrague, M.H.
Ribba, L.
Lucangioli, S.
D'Accorso, N.B.
Goyanes, S.
author_sort Parisi, M.
title Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties
title_short Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties
title_full Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties
title_fullStr Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties
title_full_unstemmed Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties
title_sort polymeric prosthetic systems for site-specific drug administration: physical and chemical properties
url http://hdl.handle.net/20.500.12110/paper_97811190_v1_n_p369_Parisi
work_keys_str_mv AT parisim polymericprostheticsystemsforsitespecificdrugadministrationphysicalandchemicalproperties
AT manzanove polymericprostheticsystemsforsitespecificdrugadministrationphysicalandchemicalproperties
AT flors polymericprostheticsystemsforsitespecificdrugadministrationphysicalandchemicalproperties
AT lissarraguemh polymericprostheticsystemsforsitespecificdrugadministrationphysicalandchemicalproperties
AT ribbal polymericprostheticsystemsforsitespecificdrugadministrationphysicalandchemicalproperties
AT lucangiolis polymericprostheticsystemsforsitespecificdrugadministrationphysicalandchemicalproperties
AT daccorsonb polymericprostheticsystemsforsitespecificdrugadministrationphysicalandchemicalproperties
AT goyaness polymericprostheticsystemsforsitespecificdrugadministrationphysicalandchemicalproperties
_version_ 1807317368075976704

Ejemplares similares