Human consciousness is supported by dynamic complex patterns of brain signal coordination
Adopting the framework of brain dynamics as a cornerstone of human consciousness, we determined whether dynamic signal coordination provides specific and generalizable patterns pertaining to conscious and unconscious states after brain damage. A dynamic pattern of coordinated and anticoordinated fun...
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| Formato: | JOUR |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_23752548_v5_n2_p_Demertzi |
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todo:paper_23752548_v5_n2_p_Demertzi2023-10-03T16:41:19Z Human consciousness is supported by dynamic complex patterns of brain signal coordination Demertzi, A. Tagliazucchi, E. Dehaene, S. Deco, G. Barttfeld, P. Raimondo, F. Martial, C. Fernández-Espejo, D. Rohaut, B. Voss, H.U. Schiff, N.D. Owen, A.M. Laureys, S. Naccache, L. Sitt, J.D. Magnetic resonance imaging Neuroimaging Complex pattern Dynamic patterns Dynamic signals Functional magnetic resonance imaging Healthy individuals Human consciousness Phase coherence Structural connectivity Coordination reactions Adopting the framework of brain dynamics as a cornerstone of human consciousness, we determined whether dynamic signal coordination provides specific and generalizable patterns pertaining to conscious and unconscious states after brain damage. A dynamic pattern of coordinated and anticoordinated functional magnetic resonance imaging signals characterized healthy individuals and minimally conscious patients. The brains of unresponsive patients showed primarily a pattern of low interareal phase coherence mainly mediated by structural connectivity, and had smaller chances to transition between patterns. The complex pattern was further corroborated in patients with covert cognition, who could perform neuroimaging mental imagery tasks, validating this pattern’s implication in consciousness. Anesthesia increased the probability of the less complex pattern to equal levels, validating its implication in unconsciousness. Our results establish that consciousness rests on the brain’s ability to sustain rich brain dynamics and pave the way for determining specific and generalizable fingerprints of conscious and unconscious states. Copyright © 2019 The Authors. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_23752548_v5_n2_p_Demertzi |
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Universidad de Buenos Aires |
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I-28 |
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R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Magnetic resonance imaging Neuroimaging Complex pattern Dynamic patterns Dynamic signals Functional magnetic resonance imaging Healthy individuals Human consciousness Phase coherence Structural connectivity Coordination reactions |
| spellingShingle |
Magnetic resonance imaging Neuroimaging Complex pattern Dynamic patterns Dynamic signals Functional magnetic resonance imaging Healthy individuals Human consciousness Phase coherence Structural connectivity Coordination reactions Demertzi, A. Tagliazucchi, E. Dehaene, S. Deco, G. Barttfeld, P. Raimondo, F. Martial, C. Fernández-Espejo, D. Rohaut, B. Voss, H.U. Schiff, N.D. Owen, A.M. Laureys, S. Naccache, L. Sitt, J.D. Human consciousness is supported by dynamic complex patterns of brain signal coordination |
| topic_facet |
Magnetic resonance imaging Neuroimaging Complex pattern Dynamic patterns Dynamic signals Functional magnetic resonance imaging Healthy individuals Human consciousness Phase coherence Structural connectivity Coordination reactions |
| description |
Adopting the framework of brain dynamics as a cornerstone of human consciousness, we determined whether dynamic signal coordination provides specific and generalizable patterns pertaining to conscious and unconscious states after brain damage. A dynamic pattern of coordinated and anticoordinated functional magnetic resonance imaging signals characterized healthy individuals and minimally conscious patients. The brains of unresponsive patients showed primarily a pattern of low interareal phase coherence mainly mediated by structural connectivity, and had smaller chances to transition between patterns. The complex pattern was further corroborated in patients with covert cognition, who could perform neuroimaging mental imagery tasks, validating this pattern’s implication in consciousness. Anesthesia increased the probability of the less complex pattern to equal levels, validating its implication in unconsciousness. Our results establish that consciousness rests on the brain’s ability to sustain rich brain dynamics and pave the way for determining specific and generalizable fingerprints of conscious and unconscious states. Copyright © 2019 The Authors. |
| format |
JOUR |
| author |
Demertzi, A. Tagliazucchi, E. Dehaene, S. Deco, G. Barttfeld, P. Raimondo, F. Martial, C. Fernández-Espejo, D. Rohaut, B. Voss, H.U. Schiff, N.D. Owen, A.M. Laureys, S. Naccache, L. Sitt, J.D. |
| author_facet |
Demertzi, A. Tagliazucchi, E. Dehaene, S. Deco, G. Barttfeld, P. Raimondo, F. Martial, C. Fernández-Espejo, D. Rohaut, B. Voss, H.U. Schiff, N.D. Owen, A.M. Laureys, S. Naccache, L. Sitt, J.D. |
| author_sort |
Demertzi, A. |
| title |
Human consciousness is supported by dynamic complex patterns of brain signal coordination |
| title_short |
Human consciousness is supported by dynamic complex patterns of brain signal coordination |
| title_full |
Human consciousness is supported by dynamic complex patterns of brain signal coordination |
| title_fullStr |
Human consciousness is supported by dynamic complex patterns of brain signal coordination |
| title_full_unstemmed |
Human consciousness is supported by dynamic complex patterns of brain signal coordination |
| title_sort |
human consciousness is supported by dynamic complex patterns of brain signal coordination |
| url |
http://hdl.handle.net/20.500.12110/paper_23752548_v5_n2_p_Demertzi |
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