Lithium decreases the effects of neuronal calcium sensor protein 1 in pedunculopontine neurons

Human postmortem studies reported increased expression of neuronal calcium sensor protein 1 (NCS-1) in the brains of some bipolar disorder patients, and reduced or aberrant gamma band activity is present in the same disorder. Bipolar disorder is characterized by sleep dysregulation, suggesting a rol...

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Detalles Bibliográficos
Autores principales: D'Onofrio, S., Urbano, F.J., Messias, E., Garcia-Rill, E.
Formato: JOUR
Materias:
Bipolar disorder
Gamma band activity
Sleep/wake
calcium channel N type
frequenin calcium sensor proteins
lithium derivative
neuroleptic agent
neuronal calcium sensor
neuropeptide
recombinant protein
voltage-dependent calcium channel (P-Q type)
animal
calcium signaling
channel gating
dose response
drug effects
female
gamma rhythm
in vitro study
kinetics
male
membrane potential
metabolism
nerve cell
newborn
pedunculopontine tegmental nucleus
Sprague Dawley rat
Animals
Animals, Newborn
Antipsychotic Agents
Calcium Channels, N-Type
Calcium Signaling
Dose-Response Relationship, Drug
Female
Gamma Rhythm
In Vitro Techniques
Ion Channel Gating
Kinetics
Lithium Compounds
Male
Membrane Potentials
Neuronal Calcium-Sensor Proteins
Neurons
Neuropeptides
Pedunculopontine Tegmental Nucleus
Rats, Sprague-Dawley
Recombinant Proteins
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_2051817X_v4_n6_p1_DOnofrio
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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