Pedunculopontine arousal system physiology - Deep brain stimulation (DBS)

This review describes the wake/sleep symptoms present in Parkinson's disease, and the role of the pedunculopontine nucleus in these symptoms. The physiology of PPN cells is important not only because it is a major element of the reticular activating system, but also because it is a novel target...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Garcia-Rill, E., Luster, B., D'Onofrio, S., Mahaffey, S., Bisagno, V., Urbano, F.J.
Formato: JOUR
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_19840659_v8_n3_p153_GarciaRill
Aporte de:
id todo:paper_19840659_v8_n3_p153_GarciaRill
record_format dspace
spelling todo:paper_19840659_v8_n3_p153_GarciaRill2023-10-03T16:37:27Z Pedunculopontine arousal system physiology - Deep brain stimulation (DBS) Garcia-Rill, E. Luster, B. D'Onofrio, S. Mahaffey, S. Bisagno, V. Urbano, F.J. Basal forebrain Calcium channels Gamma band activity Lateral hypothalamus Orexin Tuberomammillary brain depth stimulation evoked brain stem auditory response human insomnia outcome assessment Parkinson disease pedunculopontine tegmental nucleus Review sleep arousal disorder subthalamic nucleus This review describes the wake/sleep symptoms present in Parkinson's disease, and the role of the pedunculopontine nucleus in these symptoms. The physiology of PPN cells is important not only because it is a major element of the reticular activating system, but also because it is a novel target for deep brain stimulation in the treatment of gait and postural deficits in Parkinson's disease. A greater understanding of the physiology of the target nuclei within the brainstem and basal ganglia, amassed over the past decades, has enabled increasingly better patient outcomes from deep brain stimulation for movement disorders. © 2015 Brazilian Association of Sleep. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_19840659_v8_n3_p153_GarciaRill
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Basal forebrain
Calcium channels
Gamma band activity
Lateral hypothalamus
Orexin
Tuberomammillary
brain depth stimulation
evoked brain stem auditory response
human
insomnia
outcome assessment
Parkinson disease
pedunculopontine tegmental nucleus
Review
sleep arousal disorder
subthalamic nucleus
spellingShingle Basal forebrain
Calcium channels
Gamma band activity
Lateral hypothalamus
Orexin
Tuberomammillary
brain depth stimulation
evoked brain stem auditory response
human
insomnia
outcome assessment
Parkinson disease
pedunculopontine tegmental nucleus
Review
sleep arousal disorder
subthalamic nucleus
Garcia-Rill, E.
Luster, B.
D'Onofrio, S.
Mahaffey, S.
Bisagno, V.
Urbano, F.J.
Pedunculopontine arousal system physiology - Deep brain stimulation (DBS)
topic_facet Basal forebrain
Calcium channels
Gamma band activity
Lateral hypothalamus
Orexin
Tuberomammillary
brain depth stimulation
evoked brain stem auditory response
human
insomnia
outcome assessment
Parkinson disease
pedunculopontine tegmental nucleus
Review
sleep arousal disorder
subthalamic nucleus
description This review describes the wake/sleep symptoms present in Parkinson's disease, and the role of the pedunculopontine nucleus in these symptoms. The physiology of PPN cells is important not only because it is a major element of the reticular activating system, but also because it is a novel target for deep brain stimulation in the treatment of gait and postural deficits in Parkinson's disease. A greater understanding of the physiology of the target nuclei within the brainstem and basal ganglia, amassed over the past decades, has enabled increasingly better patient outcomes from deep brain stimulation for movement disorders. © 2015 Brazilian Association of Sleep.
format JOUR
author Garcia-Rill, E.
Luster, B.
D'Onofrio, S.
Mahaffey, S.
Bisagno, V.
Urbano, F.J.
author_facet Garcia-Rill, E.
Luster, B.
D'Onofrio, S.
Mahaffey, S.
Bisagno, V.
Urbano, F.J.
author_sort Garcia-Rill, E.
title Pedunculopontine arousal system physiology - Deep brain stimulation (DBS)
title_short Pedunculopontine arousal system physiology - Deep brain stimulation (DBS)
title_full Pedunculopontine arousal system physiology - Deep brain stimulation (DBS)
title_fullStr Pedunculopontine arousal system physiology - Deep brain stimulation (DBS)
title_full_unstemmed Pedunculopontine arousal system physiology - Deep brain stimulation (DBS)
title_sort pedunculopontine arousal system physiology - deep brain stimulation (dbs)
url http://hdl.handle.net/20.500.12110/paper_19840659_v8_n3_p153_GarciaRill
work_keys_str_mv AT garciarille pedunculopontinearousalsystemphysiologydeepbrainstimulationdbs
AT lusterb pedunculopontinearousalsystemphysiologydeepbrainstimulationdbs
AT donofrios pedunculopontinearousalsystemphysiologydeepbrainstimulationdbs
AT mahaffeys pedunculopontinearousalsystemphysiologydeepbrainstimulationdbs
AT bisagnov pedunculopontinearousalsystemphysiologydeepbrainstimulationdbs
AT urbanofj pedunculopontinearousalsystemphysiologydeepbrainstimulationdbs
_version_ 1807324435049349120