Pedunculopontine arousal system physiology - Deep brain stimulation (DBS)
This review describes the wake/sleep symptoms present in Parkinson's disease, and the role of the pedunculopontine nucleus in these symptoms. The physiology of PPN cells is important not only because it is a major element of the reticular activating system, but also because it is a novel target...
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Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_19840659_v8_n3_p153_GarciaRill |
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todo:paper_19840659_v8_n3_p153_GarciaRill2023-10-03T16:37:27Z Pedunculopontine arousal system physiology - Deep brain stimulation (DBS) Garcia-Rill, E. Luster, B. D'Onofrio, S. Mahaffey, S. Bisagno, V. Urbano, F.J. Basal forebrain Calcium channels Gamma band activity Lateral hypothalamus Orexin Tuberomammillary brain depth stimulation evoked brain stem auditory response human insomnia outcome assessment Parkinson disease pedunculopontine tegmental nucleus Review sleep arousal disorder subthalamic nucleus This review describes the wake/sleep symptoms present in Parkinson's disease, and the role of the pedunculopontine nucleus in these symptoms. The physiology of PPN cells is important not only because it is a major element of the reticular activating system, but also because it is a novel target for deep brain stimulation in the treatment of gait and postural deficits in Parkinson's disease. A greater understanding of the physiology of the target nuclei within the brainstem and basal ganglia, amassed over the past decades, has enabled increasingly better patient outcomes from deep brain stimulation for movement disorders. © 2015 Brazilian Association of Sleep. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_19840659_v8_n3_p153_GarciaRill |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
Basal forebrain Calcium channels Gamma band activity Lateral hypothalamus Orexin Tuberomammillary brain depth stimulation evoked brain stem auditory response human insomnia outcome assessment Parkinson disease pedunculopontine tegmental nucleus Review sleep arousal disorder subthalamic nucleus |
spellingShingle |
Basal forebrain Calcium channels Gamma band activity Lateral hypothalamus Orexin Tuberomammillary brain depth stimulation evoked brain stem auditory response human insomnia outcome assessment Parkinson disease pedunculopontine tegmental nucleus Review sleep arousal disorder subthalamic nucleus Garcia-Rill, E. Luster, B. D'Onofrio, S. Mahaffey, S. Bisagno, V. Urbano, F.J. Pedunculopontine arousal system physiology - Deep brain stimulation (DBS) |
topic_facet |
Basal forebrain Calcium channels Gamma band activity Lateral hypothalamus Orexin Tuberomammillary brain depth stimulation evoked brain stem auditory response human insomnia outcome assessment Parkinson disease pedunculopontine tegmental nucleus Review sleep arousal disorder subthalamic nucleus |
description |
This review describes the wake/sleep symptoms present in Parkinson's disease, and the role of the pedunculopontine nucleus in these symptoms. The physiology of PPN cells is important not only because it is a major element of the reticular activating system, but also because it is a novel target for deep brain stimulation in the treatment of gait and postural deficits in Parkinson's disease. A greater understanding of the physiology of the target nuclei within the brainstem and basal ganglia, amassed over the past decades, has enabled increasingly better patient outcomes from deep brain stimulation for movement disorders. © 2015 Brazilian Association of Sleep. |
format |
JOUR |
author |
Garcia-Rill, E. Luster, B. D'Onofrio, S. Mahaffey, S. Bisagno, V. Urbano, F.J. |
author_facet |
Garcia-Rill, E. Luster, B. D'Onofrio, S. Mahaffey, S. Bisagno, V. Urbano, F.J. |
author_sort |
Garcia-Rill, E. |
title |
Pedunculopontine arousal system physiology - Deep brain stimulation (DBS) |
title_short |
Pedunculopontine arousal system physiology - Deep brain stimulation (DBS) |
title_full |
Pedunculopontine arousal system physiology - Deep brain stimulation (DBS) |
title_fullStr |
Pedunculopontine arousal system physiology - Deep brain stimulation (DBS) |
title_full_unstemmed |
Pedunculopontine arousal system physiology - Deep brain stimulation (DBS) |
title_sort |
pedunculopontine arousal system physiology - deep brain stimulation (dbs) |
url |
http://hdl.handle.net/20.500.12110/paper_19840659_v8_n3_p153_GarciaRill |
work_keys_str_mv |
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_version_ |
1807324435049349120 |