Manganese superoxide dismutase gene expression is induced by Nanog and Oct4, essential pluripotent stem cells' transcription factors

Pluripotent stem cells possess complex systems that protect them from oxidative stress and ensure genomic stability, vital for their role in development. Even though it has been reported that antioxidant activity diminishes along stem cell differentiation, little is known about the transcriptional r...

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Detalles Bibliográficos
Autores principales:	Solari, C., Echegaray, C.V., Cosentino, M.S., Petrone, M.V., Waisman, A., Luzzani, C., Francia, M., Villodre, E., Lenz, G., Miriuka, S., Barañao, L., Guberman, A.
Formato:	JOUR
Materias:	manganese superoxide dismutase messenger RNA octamer transcription factor 4 short hairpin RNA transcription factor NANOG transcription factor Sox2 homeodomain protein Nanog protein, mouse Pou5f1 protein, mouse small interfering RNA superoxide dismutase animal cell Article binding site cell differentiation cell renewal cellular parameters computer model controlled study down regulation embryo embryonic stem cell gene expression profiling gene expression regulation gene identification gene repression gene sequence molecular cloning molecular dynamics mouse Nanog gene nonhuman Oct4 gene oxidative stress pluripotency pluripotent stem cell promoter region Sod2 gene transactivation transcription initiation site transcription regulation animal cell line cytology genetics induced pluripotent stem cell metabolism physiology Animals Cell Differentiation Cell Line Embryonic Stem Cells Gene Expression Regulation Gene Expression Regulation, Enzymologic Homeodomain Proteins Induced Pluripotent Stem Cells Mice Nanog Homeobox Protein Octamer Transcription Factor-3 Promoter Regions, Genetic RNA, Small Interfering Superoxide Dismutase
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_19326203_v10_n12_p_Solari
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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