Melampolides from Argentinean Acanthospermum australe
The investigation of the ethanol extract of Acanthospermum australe, collected in the province of Misiones, Argentina, yielded eight melampolides (1-8) of the acanthospermal type. Two of them, 8β-hydroxy-9α-(2-methylbutyryloxy)-14-oxo-acanthospermolide (3) and 9α-hydroxy-8β-(2-methylbutyryloxy)-14-o...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_18743900_v2_n3_p93_Sanchez |
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todo:paper_18743900_v2_n3_p93_Sanchez2023-10-03T16:34:05Z Melampolides from Argentinean Acanthospermum australe Sánchez, M. Kramer, F. Bargardi, S. Palermo, J.A. Acanthospermolides Acanthospermum australe Melampolides Sesquiterpene lactones 8beta hydroxy 9alpha (2 methylbutyryloxy) 14 oxo acanthospermolide 9alpha hydroxy 8beta (2 methylbutyryloxy) 14 oxo acanthospermolide acanthospermum australe extract melampolide plant extract unclassified drug Acanthospermum australe antimicrobial activity Argentina article artifact drug isolation drug structure Gram positive bacterium nuclear magnetic resonance priority journal shrub Acanthospermum australe Posibacteria The investigation of the ethanol extract of Acanthospermum australe, collected in the province of Misiones, Argentina, yielded eight melampolides (1-8) of the acanthospermal type. Two of them, 8β-hydroxy-9α-(2-methylbutyryloxy)-14-oxo-acanthospermolide (3) and 9α-hydroxy-8β-(2-methylbutyryloxy)-14-oxo-acanthospermolide (7) are new compounds. Two other compounds (4 and 8) have been previously reported, and the NMR data of 4 are corrected. Compounds 1, 2, 5 and 6 have not been previously reported, but are probably artifacts formed during extraction. Compounds 3, 6 and 7 showed slight antibiotic activity against Gram-positive bacteria. © 2009 Phytochemical Society of Europe. Fil:Palermo, J.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_18743900_v2_n3_p93_Sanchez |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Acanthospermolides Acanthospermum australe Melampolides Sesquiterpene lactones 8beta hydroxy 9alpha (2 methylbutyryloxy) 14 oxo acanthospermolide 9alpha hydroxy 8beta (2 methylbutyryloxy) 14 oxo acanthospermolide acanthospermum australe extract melampolide plant extract unclassified drug Acanthospermum australe antimicrobial activity Argentina article artifact drug isolation drug structure Gram positive bacterium nuclear magnetic resonance priority journal shrub Acanthospermum australe Posibacteria |
| spellingShingle |
Acanthospermolides Acanthospermum australe Melampolides Sesquiterpene lactones 8beta hydroxy 9alpha (2 methylbutyryloxy) 14 oxo acanthospermolide 9alpha hydroxy 8beta (2 methylbutyryloxy) 14 oxo acanthospermolide acanthospermum australe extract melampolide plant extract unclassified drug Acanthospermum australe antimicrobial activity Argentina article artifact drug isolation drug structure Gram positive bacterium nuclear magnetic resonance priority journal shrub Acanthospermum australe Posibacteria Sánchez, M. Kramer, F. Bargardi, S. Palermo, J.A. Melampolides from Argentinean Acanthospermum australe |
| topic_facet |
Acanthospermolides Acanthospermum australe Melampolides Sesquiterpene lactones 8beta hydroxy 9alpha (2 methylbutyryloxy) 14 oxo acanthospermolide 9alpha hydroxy 8beta (2 methylbutyryloxy) 14 oxo acanthospermolide acanthospermum australe extract melampolide plant extract unclassified drug Acanthospermum australe antimicrobial activity Argentina article artifact drug isolation drug structure Gram positive bacterium nuclear magnetic resonance priority journal shrub Acanthospermum australe Posibacteria |
| description |
The investigation of the ethanol extract of Acanthospermum australe, collected in the province of Misiones, Argentina, yielded eight melampolides (1-8) of the acanthospermal type. Two of them, 8β-hydroxy-9α-(2-methylbutyryloxy)-14-oxo-acanthospermolide (3) and 9α-hydroxy-8β-(2-methylbutyryloxy)-14-oxo-acanthospermolide (7) are new compounds. Two other compounds (4 and 8) have been previously reported, and the NMR data of 4 are corrected. Compounds 1, 2, 5 and 6 have not been previously reported, but are probably artifacts formed during extraction. Compounds 3, 6 and 7 showed slight antibiotic activity against Gram-positive bacteria. © 2009 Phytochemical Society of Europe. |
| format |
JOUR |
| author |
Sánchez, M. Kramer, F. Bargardi, S. Palermo, J.A. |
| author_facet |
Sánchez, M. Kramer, F. Bargardi, S. Palermo, J.A. |
| author_sort |
Sánchez, M. |
| title |
Melampolides from Argentinean Acanthospermum australe |
| title_short |
Melampolides from Argentinean Acanthospermum australe |
| title_full |
Melampolides from Argentinean Acanthospermum australe |
| title_fullStr |
Melampolides from Argentinean Acanthospermum australe |
| title_full_unstemmed |
Melampolides from Argentinean Acanthospermum australe |
| title_sort |
melampolides from argentinean acanthospermum australe |
| url |
http://hdl.handle.net/20.500.12110/paper_18743900_v2_n3_p93_Sanchez |
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AT sanchezm melampolidesfromargentineanacanthospermumaustrale AT kramerf melampolidesfromargentineanacanthospermumaustrale AT bargardis melampolidesfromargentineanacanthospermumaustrale AT palermoja melampolidesfromargentineanacanthospermumaustrale |
| _version_ |
1807317011518193664 |