Mice Brain nitric oxide synthase response induced by anaesthetics and other porphyrinogenic drugs

Porphyrias neuropathophysiology could be related to low levels of heme as a cofactor for nitric oxide synthase (NOS). We examined how anaesthetics and other porphyrinogenic agents affect mice NOS activity and expression. Brain response was differential depending on the cellular fraction analyzed. Mo...

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Detalles Bibliográficos
Autores principales: Lavandera, J., Batlle, A., Buzaleh, A.M.
Formato: JOUR
Materias:
Anaesthetics
Brain
Nitric oxide synthase
Porphyric neuropathy
Porphyrinogenic agent
alcohol
allylisopropylacetamide
barbital
enflurane
griseofulvin
inducible nitric oxide synthase
isoflurane
neuronal nitric oxide synthase
nitric oxide synthase
porphyrinogen
animal experiment
animal tissue
article
brain function
cell fractionation
comparative study
controlled study
enzyme activity
liver metabolism
male
mouse
nonhuman
outcome assessment
priority journal
protein expression
single drug dose
starvation
Western blotting
Anesthetics
Animals
Cell Fractionation
Cytosol
Enzyme Induction
Liver
Male
Mice
Mitochondria
Nitric Oxide Synthase
Porphyrias
Mus
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_18723128_v5_n1_p25_Lavandera
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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