Electrolytic ablation dose planning methodology
Electrolytic ablation (EA), a medical treatment increasingly used in solid tumor ablation, consists in the passage of a low direct electric current through two or more electrodes inserted in the tissue thus inducing pH fronts that destroys the tumor. The combined use of EA with a recently introduced...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | CONF |
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_16800737_v53_n_p101_Lujan |
| Aporte de: |
| id |
todo:paper_16800737_v53_n_p101_Lujan |
|---|---|
| record_format |
dspace |
| spelling |
todo:paper_16800737_v53_n_p101_Lujan2023-10-03T16:29:49Z Electrolytic ablation dose planning methodology Luján, E. Schinca, H. Olaiz, N. Urquiza, S. Molina, F.V. Turjanski, P. Marshall, G. Kramar P. Jarm T. Electrochemical treatment Electrolytic ablation In silico model In vitro model pH front tracking Tumors Ablation Electric fields Electrodes Environmental technology Tumors Direct electric currents Electrochemical treatments Front tracking In-silico models In-vitro models Medical treatment Minimally invasive Tissue ablations Tissue Electrolytic ablation (EA), a medical treatment increasingly used in solid tumor ablation, consists in the passage of a low direct electric current through two or more electrodes inserted in the tissue thus inducing pH fronts that destroys the tumor. The combined use of EA with a recently introduced one-probe two electrode device (OPTED) results in a minimally invasive tissue ablation technique. Despite its success related to low cost and minimum side effects, EA has drawbacks such as the difficulty in determining the current and time needed to assure total tumor ablation while avoiding healthy tissue intrusion. Here we introduce a realistic dose planning methodology in terms of the coulomb dosage administered and the associated pH tracking, that predicts an optimal EA/OPTED protocol treatment for a given tumor size, that is, the current and exposition time necessary to succeed in eliminating all the tumor mass while minimizing healthy tissue damage. © Springer Science+Business Media Singapore 2016. CONF info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_16800737_v53_n_p101_Lujan |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Electrochemical treatment Electrolytic ablation In silico model In vitro model pH front tracking Tumors Ablation Electric fields Electrodes Environmental technology Tumors Direct electric currents Electrochemical treatments Front tracking In-silico models In-vitro models Medical treatment Minimally invasive Tissue ablations Tissue |
| spellingShingle |
Electrochemical treatment Electrolytic ablation In silico model In vitro model pH front tracking Tumors Ablation Electric fields Electrodes Environmental technology Tumors Direct electric currents Electrochemical treatments Front tracking In-silico models In-vitro models Medical treatment Minimally invasive Tissue ablations Tissue Luján, E. Schinca, H. Olaiz, N. Urquiza, S. Molina, F.V. Turjanski, P. Marshall, G. Kramar P. Jarm T. Electrolytic ablation dose planning methodology |
| topic_facet |
Electrochemical treatment Electrolytic ablation In silico model In vitro model pH front tracking Tumors Ablation Electric fields Electrodes Environmental technology Tumors Direct electric currents Electrochemical treatments Front tracking In-silico models In-vitro models Medical treatment Minimally invasive Tissue ablations Tissue |
| description |
Electrolytic ablation (EA), a medical treatment increasingly used in solid tumor ablation, consists in the passage of a low direct electric current through two or more electrodes inserted in the tissue thus inducing pH fronts that destroys the tumor. The combined use of EA with a recently introduced one-probe two electrode device (OPTED) results in a minimally invasive tissue ablation technique. Despite its success related to low cost and minimum side effects, EA has drawbacks such as the difficulty in determining the current and time needed to assure total tumor ablation while avoiding healthy tissue intrusion. Here we introduce a realistic dose planning methodology in terms of the coulomb dosage administered and the associated pH tracking, that predicts an optimal EA/OPTED protocol treatment for a given tumor size, that is, the current and exposition time necessary to succeed in eliminating all the tumor mass while minimizing healthy tissue damage. © Springer Science+Business Media Singapore 2016. |
| format |
CONF |
| author |
Luján, E. Schinca, H. Olaiz, N. Urquiza, S. Molina, F.V. Turjanski, P. Marshall, G. Kramar P. Jarm T. |
| author_facet |
Luján, E. Schinca, H. Olaiz, N. Urquiza, S. Molina, F.V. Turjanski, P. Marshall, G. Kramar P. Jarm T. |
| author_sort |
Luján, E. |
| title |
Electrolytic ablation dose planning methodology |
| title_short |
Electrolytic ablation dose planning methodology |
| title_full |
Electrolytic ablation dose planning methodology |
| title_fullStr |
Electrolytic ablation dose planning methodology |
| title_full_unstemmed |
Electrolytic ablation dose planning methodology |
| title_sort |
electrolytic ablation dose planning methodology |
| url |
http://hdl.handle.net/20.500.12110/paper_16800737_v53_n_p101_Lujan |
| work_keys_str_mv |
AT lujane electrolyticablationdoseplanningmethodology AT schincah electrolyticablationdoseplanningmethodology AT olaizn electrolyticablationdoseplanningmethodology AT urquizas electrolyticablationdoseplanningmethodology AT molinafv electrolyticablationdoseplanningmethodology AT turjanskip electrolyticablationdoseplanningmethodology AT marshallg electrolyticablationdoseplanningmethodology AT kramarp electrolyticablationdoseplanningmethodology AT jarmt electrolyticablationdoseplanningmethodology |
| _version_ |
1807314794003300352 |