Molecular mechanisms of glucocorticoids action: From basic research to clinical implications

Glucocorticoid (GCs) hormones have pleiotropic activities in the body playing important roles in metabolism and modulating/regulating the stress and immune responses. Upon stimuli that trigger immune or inflammatory responses there is a concomitant activation of the hypothalamus-pituitary-adrenal ax...

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Detalles Bibliográficos
Autores principales: Liberman, A.C., Castro, C.N., Noguerol, M.A., Tabarrozzi, A.E.B., Druker, J., Perone, M.J., Arzt, E.
Formato: JOUR
Materias:
Glucocorticoids
Inflammation
Molecular interaction
Transcription factors
aziridine derivative
BRG1 protein
coactivator associated arginine methyltransferase 1
compound a
corticosteroid derivative
cyclic AMP responsive element binding protein binding protein
deoxyribonuclease I
glucocorticoid
glucocorticoid receptor
histone acetyltransferase
immunoglobulin enhancer binding protein
methyltransferase
mitogen activated protein kinase
nuclear receptor coactivator 2
phenylethanolamine n methyltransferase
phosphatidylinositol 3 kinase
phosphoenolpyruvate carboxykinase (GTP)
protein kinase B
protein p300
ru 24858
steroid receptor coactivator 1
transcription factor AP 1
tyrosine aminotransferase
unclassified drug
antiinflammatory activity
article
cellular immunity
chronic inflammation
conformational transition
DNA binding
drug mechanism
gene expression regulation
gene induction
gene repression
genetic transcription
hormone responsive element
human
hypothalamus hypophysis adrenal system
immune system
inflammatory disease
molecular biology
priority journal
protein DNA interaction
protein protein interaction
transactivation
transcription regulation
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_15733955_v6_n4_p371_Liberman
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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