Antiviral activity of natural and synthetic brassinosteroids

Since the discovery of brassinolide, a C28 steroid with an unusual lactone B-ring structure, more than 60 related compounds -collectively known as brassinosteroids (BRs) - have been isolated from a wide variety of plant species. Exogenous application of BRs to plants at nanomolar to micromolar conce...

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Detalles Bibliográficos
Autores principales:	Wachsman, M.B., Ramírez, J.A., Talarico, L.B., Galagovsky, L.R., Coto, C.E.
Formato:	JOUR
Materias:	Antiviral Arenaviridae Brassinosteroids derivatives Herpes simplex virus Measles virus 2 alpha 3 alpha 22,23 tetrahydroxy 5 alpha stigmastan 6 one 2 alpha 3 alpha 22,23 tetrahydroxy homo 7 oxastigmastan 6 one 2 alpha 3 alpha 5 alpha 22,23 pentahydroxystigmatan 6 one 2 alpha 3 alpha dihydroxy 5 alpha stigmast 22 en 6 one 2 alpha 3 alpha dihydroxy 6 alpha fluoro 5 alpha stigmast 22 ene 2,3,22,23 bisacetyliden 2 alpha 3 alpha 22,23 tetrahydroxy 5 alpha sigmastan 6 one 3 alpha 22,23 trihydroxy 5 alpha stigmastan 6 one 3 alpha fluoro 22,23 dihydroxy 5 alpha stigmastan 6 one 3 beta 5 alpha dihydroxystigmast 22 en 6 one 3 beta acetoxy 22,23 dihydroxy 5 alpha stigmastan 6 one 3 beta acetoxy 22,23 trihydroxy 5 alpha stigmastan 6 one 3 beta acetoxy 5 alpha 22,23 trihydrostigmastan 6 one 3 beta bromo 5 alpha 22,23 trihydroxystigmastan 6 one 3 beta bromo 5 alpha hydroxystigmast 22 en 6 one 3 beta fluoro 5 alpha 22,23 trihydroxystigmastan 6 one aciclovir brassinolide brassinosteroid epoxide foscarnet lactone orthoesterol A orthoesterol B orthoesterol C phytosterol ribavirin stigmasterol unclassified drug unindexed drug weibensterol A weibensterol B antiviral activity Arenavirus cell division chemical analysis DNA virus drug classification drug isolation drug selectivity drug synthesis enzyme activity gene expression genetic analysis Herpes simplex virus 1 Herpes simplex virus 2 Junin virus nonhuman Paramyxovirus plant plant development plant stress review RNA virus root growth stem elongation stereochemistry structure activity relation
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_15680126_v3_n2_p163_Wachsman
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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