Genetic structure of Triatoma infestans populations in rural communities of Santiago del Estero, northern Argentina
To gain an understanding of the genetic structure and dispersal dynamics of Triatoma infestans populations, we analyzed the multilocus genotype of 10 microsatellite loci for 352 T. infestans collected in 21 houses of 11 rural communities in October 2002. Genetic structure was analyzed at the communi...
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todo:paper_15671348_v8_n6_p835_Marcet2023-10-03T16:26:33Z Genetic structure of Triatoma infestans populations in rural communities of Santiago del Estero, northern Argentina Marcet, P.L. Mora, M.S. Cutrera, A.P. Jones, L. Gürtler, R.E. Kitron, U. Dotson, E.M. Chagas disease Microsatellite loci Population structure Triatoma infestans Vector control Argentina article controlled study DNA extraction female flight gene amplification gene cluster gene linkage disequilibrium gene locus genetic isolation by distance genetic variability genotype geography immigrant infestation insect genetics male nonhuman polymerase chain reaction population dispersal priority journal rural area sex difference Triatoma infestans vector control walking Analysis of Variance Animals Argentina Bayes Theorem Chagas Disease Female Genetic Variation Humans Insect Control Insect Vectors Insecticides Linkage Disequilibrium Male Microsatellite Repeats Monte Carlo Method Polymerase Chain Reaction Population Dynamics Rural Population Sex Distribution Triatoma Triatoma infestans To gain an understanding of the genetic structure and dispersal dynamics of Triatoma infestans populations, we analyzed the multilocus genotype of 10 microsatellite loci for 352 T. infestans collected in 21 houses of 11 rural communities in October 2002. Genetic structure was analyzed at the community and house compound levels. Analysis revealed that vector control actions affected the genetic structure of T. infestans populations. Bug populations from communities under sustained vector control (core area) were highly structured and genetic differentiation between neighboring house compounds was significant. In contrast, bug populations from communities with sporadic vector control actions were more homogeneous and lacked defined genetic clusters. Genetic differentiation between population pairs did not fit a model of isolation by distance at the microgeographical level. Evidence consistent with flight or walking bug dispersal was detected within and among communities, dispersal was more female-biased in the core area and results suggested that houses received immigrants from more than one source. Putative sources and mechanisms of re-infestation are described. These data may be use to design improved vector control strategies. Fil:Marcet, P.L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Gürtler, R.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_15671348_v8_n6_p835_Marcet |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
Chagas disease Microsatellite loci Population structure Triatoma infestans Vector control Argentina article controlled study DNA extraction female flight gene amplification gene cluster gene linkage disequilibrium gene locus genetic isolation by distance genetic variability genotype geography immigrant infestation insect genetics male nonhuman polymerase chain reaction population dispersal priority journal rural area sex difference Triatoma infestans vector control walking Analysis of Variance Animals Argentina Bayes Theorem Chagas Disease Female Genetic Variation Humans Insect Control Insect Vectors Insecticides Linkage Disequilibrium Male Microsatellite Repeats Monte Carlo Method Polymerase Chain Reaction Population Dynamics Rural Population Sex Distribution Triatoma Triatoma infestans |
spellingShingle |
Chagas disease Microsatellite loci Population structure Triatoma infestans Vector control Argentina article controlled study DNA extraction female flight gene amplification gene cluster gene linkage disequilibrium gene locus genetic isolation by distance genetic variability genotype geography immigrant infestation insect genetics male nonhuman polymerase chain reaction population dispersal priority journal rural area sex difference Triatoma infestans vector control walking Analysis of Variance Animals Argentina Bayes Theorem Chagas Disease Female Genetic Variation Humans Insect Control Insect Vectors Insecticides Linkage Disequilibrium Male Microsatellite Repeats Monte Carlo Method Polymerase Chain Reaction Population Dynamics Rural Population Sex Distribution Triatoma Triatoma infestans Marcet, P.L. Mora, M.S. Cutrera, A.P. Jones, L. Gürtler, R.E. Kitron, U. Dotson, E.M. Genetic structure of Triatoma infestans populations in rural communities of Santiago del Estero, northern Argentina |
topic_facet |
Chagas disease Microsatellite loci Population structure Triatoma infestans Vector control Argentina article controlled study DNA extraction female flight gene amplification gene cluster gene linkage disequilibrium gene locus genetic isolation by distance genetic variability genotype geography immigrant infestation insect genetics male nonhuman polymerase chain reaction population dispersal priority journal rural area sex difference Triatoma infestans vector control walking Analysis of Variance Animals Argentina Bayes Theorem Chagas Disease Female Genetic Variation Humans Insect Control Insect Vectors Insecticides Linkage Disequilibrium Male Microsatellite Repeats Monte Carlo Method Polymerase Chain Reaction Population Dynamics Rural Population Sex Distribution Triatoma Triatoma infestans |
description |
To gain an understanding of the genetic structure and dispersal dynamics of Triatoma infestans populations, we analyzed the multilocus genotype of 10 microsatellite loci for 352 T. infestans collected in 21 houses of 11 rural communities in October 2002. Genetic structure was analyzed at the community and house compound levels. Analysis revealed that vector control actions affected the genetic structure of T. infestans populations. Bug populations from communities under sustained vector control (core area) were highly structured and genetic differentiation between neighboring house compounds was significant. In contrast, bug populations from communities with sporadic vector control actions were more homogeneous and lacked defined genetic clusters. Genetic differentiation between population pairs did not fit a model of isolation by distance at the microgeographical level. Evidence consistent with flight or walking bug dispersal was detected within and among communities, dispersal was more female-biased in the core area and results suggested that houses received immigrants from more than one source. Putative sources and mechanisms of re-infestation are described. These data may be use to design improved vector control strategies. |
format |
JOUR |
author |
Marcet, P.L. Mora, M.S. Cutrera, A.P. Jones, L. Gürtler, R.E. Kitron, U. Dotson, E.M. |
author_facet |
Marcet, P.L. Mora, M.S. Cutrera, A.P. Jones, L. Gürtler, R.E. Kitron, U. Dotson, E.M. |
author_sort |
Marcet, P.L. |
title |
Genetic structure of Triatoma infestans populations in rural communities of Santiago del Estero, northern Argentina |
title_short |
Genetic structure of Triatoma infestans populations in rural communities of Santiago del Estero, northern Argentina |
title_full |
Genetic structure of Triatoma infestans populations in rural communities of Santiago del Estero, northern Argentina |
title_fullStr |
Genetic structure of Triatoma infestans populations in rural communities of Santiago del Estero, northern Argentina |
title_full_unstemmed |
Genetic structure of Triatoma infestans populations in rural communities of Santiago del Estero, northern Argentina |
title_sort |
genetic structure of triatoma infestans populations in rural communities of santiago del estero, northern argentina |
url |
http://hdl.handle.net/20.500.12110/paper_15671348_v8_n6_p835_Marcet |
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