Intramolecular Phl=O mediated copper-catalyzed aziridination of unsaturated sulfamates: A new direct access to polysubstituted amines from simple homoallylic alcohols

(Matrix presented) Olefinic sulfamates derived from primary and secondary alcohols undergo intramolecular copper-catalyzed aziridination in the presence of iodosylbenzene to afford novel bicyclic fused aziridines. The latter were opened by various nucleophiles to give the corresponding substituted c...

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Autores principales:	Duran, F., Leman, L., Ghini, A., Burton, G., Dauban, P., Dodd, R.H.
Formato:	JOUR
Materias:	alcohol derivative amine aziridine derivative biological factor copper sulfamic acid sulfonic acid derivative article catalysis chemistry cyclization methodology synthesis Alcohols Amines Aziridines Biological Factors Catalysis Chemistry, Pharmaceutical Copper Cyclization Sulfonic Acids
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_15237060_v4_n15_p2481_Duran
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_15237060_v4_n15_p2481_Duran
record_format	dspace
spelling	todo:paper_15237060_v4_n15_p2481_Duran2023-10-03T16:20:54Z Intramolecular Phl=O mediated copper-catalyzed aziridination of unsaturated sulfamates: A new direct access to polysubstituted amines from simple homoallylic alcohols Duran, F. Leman, L. Ghini, A. Burton, G. Dauban, P. Dodd, R.H. alcohol derivative amine aziridine derivative biological factor copper sulfamic acid sulfonic acid derivative article catalysis chemistry cyclization methodology synthesis Alcohols Amines Aziridines Biological Factors Catalysis Chemistry, Pharmaceutical Copper Cyclization Sulfonic Acids (Matrix presented) Olefinic sulfamates derived from primary and secondary alcohols undergo intramolecular copper-catalyzed aziridination in the presence of iodosylbenzene to afford novel bicyclic fused aziridines. The latter were opened by various nucleophiles to give the corresponding substituted cyclic sulfamates, which in turn reacted, after nitrogen activation, with a second nucleophile at the carbon atom bearing the oxygen atom. Concomitant removal of the sulfonyloxy moiety thus gave access to polysubstituted amines. Fil:Duran, F. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Ghini, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Burton, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_15237060_v4_n15_p2481_Duran
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	alcohol derivative amine aziridine derivative biological factor copper sulfamic acid sulfonic acid derivative article catalysis chemistry cyclization methodology synthesis Alcohols Amines Aziridines Biological Factors Catalysis Chemistry, Pharmaceutical Copper Cyclization Sulfonic Acids
spellingShingle	alcohol derivative amine aziridine derivative biological factor copper sulfamic acid sulfonic acid derivative article catalysis chemistry cyclization methodology synthesis Alcohols Amines Aziridines Biological Factors Catalysis Chemistry, Pharmaceutical Copper Cyclization Sulfonic Acids Duran, F. Leman, L. Ghini, A. Burton, G. Dauban, P. Dodd, R.H. Intramolecular Phl=O mediated copper-catalyzed aziridination of unsaturated sulfamates: A new direct access to polysubstituted amines from simple homoallylic alcohols
topic_facet	alcohol derivative amine aziridine derivative biological factor copper sulfamic acid sulfonic acid derivative article catalysis chemistry cyclization methodology synthesis Alcohols Amines Aziridines Biological Factors Catalysis Chemistry, Pharmaceutical Copper Cyclization Sulfonic Acids
description	(Matrix presented) Olefinic sulfamates derived from primary and secondary alcohols undergo intramolecular copper-catalyzed aziridination in the presence of iodosylbenzene to afford novel bicyclic fused aziridines. The latter were opened by various nucleophiles to give the corresponding substituted cyclic sulfamates, which in turn reacted, after nitrogen activation, with a second nucleophile at the carbon atom bearing the oxygen atom. Concomitant removal of the sulfonyloxy moiety thus gave access to polysubstituted amines.
format	JOUR
author	Duran, F. Leman, L. Ghini, A. Burton, G. Dauban, P. Dodd, R.H.
author_facet	Duran, F. Leman, L. Ghini, A. Burton, G. Dauban, P. Dodd, R.H.
author_sort	Duran, F.
title	Intramolecular Phl=O mediated copper-catalyzed aziridination of unsaturated sulfamates: A new direct access to polysubstituted amines from simple homoallylic alcohols
title_short	Intramolecular Phl=O mediated copper-catalyzed aziridination of unsaturated sulfamates: A new direct access to polysubstituted amines from simple homoallylic alcohols
title_full	Intramolecular Phl=O mediated copper-catalyzed aziridination of unsaturated sulfamates: A new direct access to polysubstituted amines from simple homoallylic alcohols
title_fullStr	Intramolecular Phl=O mediated copper-catalyzed aziridination of unsaturated sulfamates: A new direct access to polysubstituted amines from simple homoallylic alcohols
title_full_unstemmed	Intramolecular Phl=O mediated copper-catalyzed aziridination of unsaturated sulfamates: A new direct access to polysubstituted amines from simple homoallylic alcohols
title_sort	intramolecular phl=o mediated copper-catalyzed aziridination of unsaturated sulfamates: a new direct access to polysubstituted amines from simple homoallylic alcohols
url	http://hdl.handle.net/20.500.12110/paper_15237060_v4_n15_p2481_Duran
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Intramolecular Phl=O mediated copper-catalyzed aziridination of unsaturated sulfamates: A new direct access to polysubstituted amines from simple homoallylic alcohols

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