An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride

An efficient route for large-scale preparation of lapyrium chloride, a broad-spectrum antimicrobial surfactant, was developed from chloroacetic acid in four steps, three of them enzymatic. Due to the chemoselective behavior of the biocatalysts, lapyrium chloride was obtained in a high degree of puri...

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Detalles Bibliográficos
Autores principales: Rustoy, E.M., Baldessari, A.
Formato: JOUR
Materias:
Aminolysis
Bactericide
Enzyme-catalyzed acylation
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_1434193X_v_n21_p4628_Rustoy
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
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spelling todo:paper_1434193X_v_n21_p4628_Rustoy2023-10-03T16:14:17Z An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride Rustoy, E.M. Baldessari, A. Aminolysis Bactericide Enzyme-catalyzed acylation An efficient route for large-scale preparation of lapyrium chloride, a broad-spectrum antimicrobial surfactant, was developed from chloroacetic acid in four steps, three of them enzymatic. Due to the chemoselective behavior of the biocatalysts, lapyrium chloride was obtained in a high degree of purity and yield, from mild reaction conditions and following a low environmental impact methodology. © Wiley-VCH Verlag GmbH & Co. KGaA, 2005. Fil:Rustoy, E.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Baldessari, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_1434193X_v_n21_p4628_Rustoy
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Aminolysis
Bactericide
Enzyme-catalyzed acylation
spellingShingle Aminolysis
Bactericide
Enzyme-catalyzed acylation
Rustoy, E.M.
Baldessari, A.
An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride
topic_facet Aminolysis
Bactericide
Enzyme-catalyzed acylation
description An efficient route for large-scale preparation of lapyrium chloride, a broad-spectrum antimicrobial surfactant, was developed from chloroacetic acid in four steps, three of them enzymatic. Due to the chemoselective behavior of the biocatalysts, lapyrium chloride was obtained in a high degree of purity and yield, from mild reaction conditions and following a low environmental impact methodology. © Wiley-VCH Verlag GmbH & Co. KGaA, 2005.
format JOUR
author Rustoy, E.M.
Baldessari, A.
author_facet Rustoy, E.M.
Baldessari, A.
author_sort Rustoy, E.M.
title An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride
title_short An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride
title_full An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride
title_fullStr An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride
title_full_unstemmed An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride
title_sort efficient chemoenzymatic synthesis of the bactericide lapyrium chloride
url http://hdl.handle.net/20.500.12110/paper_1434193X_v_n21_p4628_Rustoy
work_keys_str_mv AT rustoyem anefficientchemoenzymaticsynthesisofthebactericidelapyriumchloride
AT baldessaria anefficientchemoenzymaticsynthesisofthebactericidelapyriumchloride
AT rustoyem efficientchemoenzymaticsynthesisofthebactericidelapyriumchloride
AT baldessaria efficientchemoenzymaticsynthesisofthebactericidelapyriumchloride
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