The Critical Role of Intrinsic Membrane Oscillations

Intrinsic, rhythmic subthreshold oscillations have been described in neurons of regions throughout the brain and have been found to influence the timing of action potentials induced by synaptic inputs. Some oscillations are sodium channel-dependent while others are calcium channel-dependent. These o...

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Autores principales:	Lee, S.-H., Urbano, F.J., Garcia-Rill, E.
Formato:	INPR
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_1424862X_v_n_p66_Lee
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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spelling	todo:paper_1424862X_v_n_p66_Lee2023-10-03T16:13:50Z The Critical Role of Intrinsic Membrane Oscillations Lee, S.-H. Urbano, F.J. Garcia-Rill, E. Intrinsic, rhythmic subthreshold oscillations have been described in neurons of regions throughout the brain and have been found to influence the timing of action potentials induced by synaptic inputs. Some oscillations are sodium channel-dependent while others are calcium channel-dependent. These oscillations allow neurons to fire coherently at preferred frequencies and represent the main mechanism for maintaining high frequency network activity, especially in the cortex. Because cortical circuits are incapable of maintaining high frequency activity in the gamma range for prolonged periods, those processes dependent on continuous gamma band activity are subserved by subthreshold oscillations. As such, intrinsic oscillations, coupled with synaptic circuits, are essential to prolonged maintenance of such functions as sensory perception and "binding", problem solving, memory, waking, and rapid eye movement (REM) sleep. © 2018 The Author(s). Published by S. Karger AG, Basel. INPR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_1424862X_v_n_p66_Lee
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
description	Intrinsic, rhythmic subthreshold oscillations have been described in neurons of regions throughout the brain and have been found to influence the timing of action potentials induced by synaptic inputs. Some oscillations are sodium channel-dependent while others are calcium channel-dependent. These oscillations allow neurons to fire coherently at preferred frequencies and represent the main mechanism for maintaining high frequency network activity, especially in the cortex. Because cortical circuits are incapable of maintaining high frequency activity in the gamma range for prolonged periods, those processes dependent on continuous gamma band activity are subserved by subthreshold oscillations. As such, intrinsic oscillations, coupled with synaptic circuits, are essential to prolonged maintenance of such functions as sensory perception and "binding", problem solving, memory, waking, and rapid eye movement (REM) sleep. © 2018 The Author(s). Published by S. Karger AG, Basel.
format	INPR
author	Lee, S.-H. Urbano, F.J. Garcia-Rill, E.
spellingShingle	Lee, S.-H. Urbano, F.J. Garcia-Rill, E. The Critical Role of Intrinsic Membrane Oscillations
author_facet	Lee, S.-H. Urbano, F.J. Garcia-Rill, E.
author_sort	Lee, S.-H.
title	The Critical Role of Intrinsic Membrane Oscillations
title_short	The Critical Role of Intrinsic Membrane Oscillations
title_full	The Critical Role of Intrinsic Membrane Oscillations
title_fullStr	The Critical Role of Intrinsic Membrane Oscillations
title_full_unstemmed	The Critical Role of Intrinsic Membrane Oscillations
title_sort	critical role of intrinsic membrane oscillations
url	http://hdl.handle.net/20.500.12110/paper_1424862X_v_n_p66_Lee
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The Critical Role of Intrinsic Membrane Oscillations

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