Bilirubin: Its role in cytoprotection against oxidative stress
Bilirubin, the end product of heme catabolism in mammals, is generally regarded as a potentially cytotoxic, lipid-soluble waste product that needs to be excreted. However, in the last 10 years, in vitro and in vivo studies, have demonstrated that bilirubin exhibits potent anti-oxidant properties pre...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_13572725_v34_n3_p216_Tomaro |
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todo:paper_13572725_v34_n3_p216_Tomaro2023-10-03T16:10:30Z Bilirubin: Its role in cytoprotection against oxidative stress Tomaro, M.L. Batlle, A.M.D.C. Anti-oxidant defenses Bilirubin Heme catabolism Heme oxygenase Oxidative stress bilirubin article catabolism cell damage cell protection chemical structure human mammal oxidation oxidative stress physiology Mammalia Bilirubin, the end product of heme catabolism in mammals, is generally regarded as a potentially cytotoxic, lipid-soluble waste product that needs to be excreted. However, in the last 10 years, in vitro and in vivo studies, have demonstrated that bilirubin exhibits potent anti-oxidant properties preventing the oxidative damage triggered by a wide range of oxidant-related stimuli. Therefore, the idea of a beneficial and physiological role for bilirubin in cytoprotection against short and long-lasting oxidant-mediated cell injury is highlighted here. © 2002 Elsevier Science Ltd. All rights reserved. Fil:Batlle, A.M.D.C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_13572725_v34_n3_p216_Tomaro |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Anti-oxidant defenses Bilirubin Heme catabolism Heme oxygenase Oxidative stress bilirubin article catabolism cell damage cell protection chemical structure human mammal oxidation oxidative stress physiology Mammalia |
| spellingShingle |
Anti-oxidant defenses Bilirubin Heme catabolism Heme oxygenase Oxidative stress bilirubin article catabolism cell damage cell protection chemical structure human mammal oxidation oxidative stress physiology Mammalia Tomaro, M.L. Batlle, A.M.D.C. Bilirubin: Its role in cytoprotection against oxidative stress |
| topic_facet |
Anti-oxidant defenses Bilirubin Heme catabolism Heme oxygenase Oxidative stress bilirubin article catabolism cell damage cell protection chemical structure human mammal oxidation oxidative stress physiology Mammalia |
| description |
Bilirubin, the end product of heme catabolism in mammals, is generally regarded as a potentially cytotoxic, lipid-soluble waste product that needs to be excreted. However, in the last 10 years, in vitro and in vivo studies, have demonstrated that bilirubin exhibits potent anti-oxidant properties preventing the oxidative damage triggered by a wide range of oxidant-related stimuli. Therefore, the idea of a beneficial and physiological role for bilirubin in cytoprotection against short and long-lasting oxidant-mediated cell injury is highlighted here. © 2002 Elsevier Science Ltd. All rights reserved. |
| format |
JOUR |
| author |
Tomaro, M.L. Batlle, A.M.D.C. |
| author_facet |
Tomaro, M.L. Batlle, A.M.D.C. |
| author_sort |
Tomaro, M.L. |
| title |
Bilirubin: Its role in cytoprotection against oxidative stress |
| title_short |
Bilirubin: Its role in cytoprotection against oxidative stress |
| title_full |
Bilirubin: Its role in cytoprotection against oxidative stress |
| title_fullStr |
Bilirubin: Its role in cytoprotection against oxidative stress |
| title_full_unstemmed |
Bilirubin: Its role in cytoprotection against oxidative stress |
| title_sort |
bilirubin: its role in cytoprotection against oxidative stress |
| url |
http://hdl.handle.net/20.500.12110/paper_13572725_v34_n3_p216_Tomaro |
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AT tomaroml bilirubinitsroleincytoprotectionagainstoxidativestress AT batlleamdc bilirubinitsroleincytoprotectionagainstoxidativestress |
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1807322836851752960 |