Regulation of eIF4F Translation Initiation Complex by the Peptidyl Prolyl Isomerase FKBP7 in Taxane-resistant Prostate Cancer

Purpose: Targeted therapies that use the signaling path-characterize the function of human FKBP7 and explore its ways involved in prostate cancer are required to overcome role in cancer. We discovered that FKBP7 was upregulated chemoresistance and improve treatment outcomes for men. in human prostat...

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Detalles Bibliográficos
Autores principales: Garrido, M.F., Martin, N.J.-P., Bertrand, M., Gaudin, C., Commo, F.E., Kalaany, N.E., Nakouzi, N.A., Fazli, L., Nery, E.D., Camonis, J., Perez, F., Lerondel, S., Le Pape, A., Compagno, D., Gleave, M., Loriot, Y., Desaubry, L., Vagner, S., Fizazi, K., Chauchereau, A.
Formato: JOUR
Materias:
cabazitaxel
docetaxel
initiation factor 4F
initiation factor 4FG
peptidylprolyl isomerase
peptidylprolyl isomerase FKBP7
short hairpin RNA
small interfering RNA
taxane derivative
unclassified drug
animal experiment
animal model
animal tissue
Article
cancer resistance
carcinogenicity
cell proliferation
cell survival
controlled study
drug targeting
enzyme activity
gene expression regulation
gene knockdown
gene silencing
genetic transfection
human
human cell
human tissue
in vitro study
in vivo study
intracellular signaling
male
mass spectrometry
nonhuman
priority journal
prostate cancer cell line
protein expression
protein protein interaction
tissue microarray
translation initiation
translation regulation
tumor xenograft
upregulation
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_10780432_v25_n2_p710_Garrido
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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