Positive modulation of a neutral declarative memory by a threatening social event

Memories can be altered by negative or arousing experiences due to the activation of the stress-responsive sympatho-adrenal-medullary axis (SYM). Here, we used a neutral declarative memory that was acquired during multi-trial training to determine the effect of a threatening event on memory without...

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Detalles Bibliográficos
Autores principales:	Fernández, R.S., Bavassi, L., Campos, J., Allegri, R.F., Molina, V.A., Forcato, C., Pedreira, M.E.
Formato:	JOUR
Materias:	Autonomic nervous system Memory improvement Memory persistence Neutral declarative memory Pre-learning stress Psychosocial stress adult Article controlled study declarative memory emotionality experimental study female human human experiment hypothalamus hypophysis adrenal system life event life threat male memory consolidation mental performance neuroanatomy neuromodulation normal human social behavior sympatho-adrenal-medullary axis adrenergic system affect blood pressure heart rate hypophysis adrenal system hypothalamus hypophysis system memory mental stress metabolism physiology speech young adult hydrocortisone Adult Affect Blood Pressure Female Heart Rate Humans Hydrocortisone Hypothalamo-Hypophyseal System Male Memory Pituitary-Adrenal System Speech Stress, Psychological Sympathetic Nervous System Young Adult
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_10747427_v126_n_p56_Fernandez
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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spelling	todo:paper_10747427_v126_n_p56_Fernandez2023-10-03T16:03:00Z Positive modulation of a neutral declarative memory by a threatening social event Fernández, R.S. Bavassi, L. Campos, J. Allegri, R.F. Molina, V.A. Forcato, C. Pedreira, M.E. Autonomic nervous system Memory improvement Memory persistence Neutral declarative memory Pre-learning stress Psychosocial stress adult Article controlled study declarative memory emotionality experimental study female human human experiment hypothalamus hypophysis adrenal system life event life threat male memory consolidation mental performance neuroanatomy neuromodulation normal human social behavior sympatho-adrenal-medullary axis adrenergic system affect blood pressure heart rate hypophysis adrenal system hypothalamus hypophysis system memory mental stress metabolism physiology speech young adult hydrocortisone Adult Affect Blood Pressure Female Heart Rate Humans Hydrocortisone Hypothalamo-Hypophyseal System Male Memory Pituitary-Adrenal System Speech Stress, Psychological Sympathetic Nervous System Young Adult Memories can be altered by negative or arousing experiences due to the activation of the stress-responsive sympatho-adrenal-medullary axis (SYM). Here, we used a neutral declarative memory that was acquired during multi-trial training to determine the effect of a threatening event on memory without emotional valence. To this end, participants received a new threatening social protocol before learning pairs of meaningless syllables and were tested either 15. min, 2. days or 8. days after acquisition. We first demonstrated that this threatening social situation activates not only the SYM axis (Experiment 1) and the hypothalamus-pituitary-adrenal axis (HPA; Experiment 2), but also, it improves the acquisition or early consolidation of the syllable pairs (Experiment 3). This improvement is not a transient effect; it can be observed after the memory is consolidated. Furthermore, this modulation increases the persistence of memory (Experiment 4). Thus, it is possible to affect memories with specific events that contain unrelated content and a different valence. © 2015 Elsevier Inc. Fil:Bavassi, L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Forcato, C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Pedreira, M.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_10747427_v126_n_p56_Fernandez
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Autonomic nervous system Memory improvement Memory persistence Neutral declarative memory Pre-learning stress Psychosocial stress adult Article controlled study declarative memory emotionality experimental study female human human experiment hypothalamus hypophysis adrenal system life event life threat male memory consolidation mental performance neuroanatomy neuromodulation normal human social behavior sympatho-adrenal-medullary axis adrenergic system affect blood pressure heart rate hypophysis adrenal system hypothalamus hypophysis system memory mental stress metabolism physiology speech young adult hydrocortisone Adult Affect Blood Pressure Female Heart Rate Humans Hydrocortisone Hypothalamo-Hypophyseal System Male Memory Pituitary-Adrenal System Speech Stress, Psychological Sympathetic Nervous System Young Adult
spellingShingle	Autonomic nervous system Memory improvement Memory persistence Neutral declarative memory Pre-learning stress Psychosocial stress adult Article controlled study declarative memory emotionality experimental study female human human experiment hypothalamus hypophysis adrenal system life event life threat male memory consolidation mental performance neuroanatomy neuromodulation normal human social behavior sympatho-adrenal-medullary axis adrenergic system affect blood pressure heart rate hypophysis adrenal system hypothalamus hypophysis system memory mental stress metabolism physiology speech young adult hydrocortisone Adult Affect Blood Pressure Female Heart Rate Humans Hydrocortisone Hypothalamo-Hypophyseal System Male Memory Pituitary-Adrenal System Speech Stress, Psychological Sympathetic Nervous System Young Adult Fernández, R.S. Bavassi, L. Campos, J. Allegri, R.F. Molina, V.A. Forcato, C. Pedreira, M.E. Positive modulation of a neutral declarative memory by a threatening social event
topic_facet	Autonomic nervous system Memory improvement Memory persistence Neutral declarative memory Pre-learning stress Psychosocial stress adult Article controlled study declarative memory emotionality experimental study female human human experiment hypothalamus hypophysis adrenal system life event life threat male memory consolidation mental performance neuroanatomy neuromodulation normal human social behavior sympatho-adrenal-medullary axis adrenergic system affect blood pressure heart rate hypophysis adrenal system hypothalamus hypophysis system memory mental stress metabolism physiology speech young adult hydrocortisone Adult Affect Blood Pressure Female Heart Rate Humans Hydrocortisone Hypothalamo-Hypophyseal System Male Memory Pituitary-Adrenal System Speech Stress, Psychological Sympathetic Nervous System Young Adult
description	Memories can be altered by negative or arousing experiences due to the activation of the stress-responsive sympatho-adrenal-medullary axis (SYM). Here, we used a neutral declarative memory that was acquired during multi-trial training to determine the effect of a threatening event on memory without emotional valence. To this end, participants received a new threatening social protocol before learning pairs of meaningless syllables and were tested either 15. min, 2. days or 8. days after acquisition. We first demonstrated that this threatening social situation activates not only the SYM axis (Experiment 1) and the hypothalamus-pituitary-adrenal axis (HPA; Experiment 2), but also, it improves the acquisition or early consolidation of the syllable pairs (Experiment 3). This improvement is not a transient effect; it can be observed after the memory is consolidated. Furthermore, this modulation increases the persistence of memory (Experiment 4). Thus, it is possible to affect memories with specific events that contain unrelated content and a different valence. © 2015 Elsevier Inc.
format	JOUR
author	Fernández, R.S. Bavassi, L. Campos, J. Allegri, R.F. Molina, V.A. Forcato, C. Pedreira, M.E.
author_facet	Fernández, R.S. Bavassi, L. Campos, J. Allegri, R.F. Molina, V.A. Forcato, C. Pedreira, M.E.
author_sort	Fernández, R.S.
title	Positive modulation of a neutral declarative memory by a threatening social event
title_short	Positive modulation of a neutral declarative memory by a threatening social event
title_full	Positive modulation of a neutral declarative memory by a threatening social event
title_fullStr	Positive modulation of a neutral declarative memory by a threatening social event
title_full_unstemmed	Positive modulation of a neutral declarative memory by a threatening social event
title_sort	positive modulation of a neutral declarative memory by a threatening social event
url	http://hdl.handle.net/20.500.12110/paper_10747427_v126_n_p56_Fernandez
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Positive modulation of a neutral declarative memory by a threatening social event

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