Effects of intra-aortic counterpulsation on aortic wall energetics and damping: In vivo experiments

Intra-aortic balloon pumping (IABP) could modify the arterial biomechanics; however, its effects on arterial wall properties have not been fully explored. This dynamical study was designed to characterize the pressure-dependent and smooth muscle-dependent effects of IABP on aortic wall energetics in...

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Autores principales:	Fischer, E.I.C., Bia, D., Camus, J.M., Zócalo, Y., De Forteza, E., Armentano, R.L.
Formato:	JOUR
Materias:	Cardiology Energy dissipation Physiological models Pressure effects Aortic pressure Aortic wall energetics Intra-aortic balloon pumping (IABP) Intra-aortic counterpulsation Biomechanics animal cell animal experiment animal model animal tissue aorta balloon aorta pressure aorta wall article biomechanics controlled study counterpulsation in vivo study mathematical computing nonhuman pulse wave sheep smooth muscle Animals Aorta Cardiac Output Coronary Circulation Coronary Vessels Counterpulsation Disease Models, Animal Heart Failure Heart Rate Intra-Aortic Balloon Pumping Models, Biological Pressure Sheep Time Factors
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_10582916_v54_n1_p44_Fischer
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_10582916_v54_n1_p44_Fischer
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spelling	todo:paper_10582916_v54_n1_p44_Fischer2023-10-03T16:00:56Z Effects of intra-aortic counterpulsation on aortic wall energetics and damping: In vivo experiments Fischer, E.I.C. Bia, D. Camus, J.M. Zócalo, Y. De Forteza, E. Armentano, R.L. Cardiology Energy dissipation Physiological models Pressure effects Aortic pressure Aortic wall energetics Intra-aortic balloon pumping (IABP) Intra-aortic counterpulsation Biomechanics animal cell animal experiment animal model animal tissue aorta balloon aorta pressure aorta wall article biomechanics controlled study counterpulsation in vivo study mathematical computing nonhuman pulse wave sheep smooth muscle Animals Aorta Cardiac Output Cardiology Coronary Circulation Coronary Vessels Counterpulsation Disease Models, Animal Heart Failure Heart Rate Intra-Aortic Balloon Pumping Models, Biological Pressure Sheep Time Factors Intra-aortic balloon pumping (IABP) could modify the arterial biomechanics; however, its effects on arterial wall properties have not been fully explored. This dynamical study was designed to characterize the pressure-dependent and smooth muscle-dependent effects of IABP on aortic wall energetics in an in vivo animal model. Intra-aortic balloon pumping (1:2) was performed in six anesthetized sheep in which aortic pressure and diameter signals were measured in basal, augmented (during balloon inflation), and assisted (postaugmented) beats. Energy dissipation values in augmented and assisted beats were significantly higher than those observed in basal state (p < 0.05). Assisted beats showed a significant increase of wall damping with respect to basal and augmented beats (p < 0.05). Intra-aortic balloon pumping resulted in a significant increase of pulse wave velocity (p < 0.05) in augmented beats with respect to basal state (6.3 ± 0.8 vs. 5.2 ± 0.5 m·s); whereas values observed in assisted beats were significantly (p < 0.05) lower than those observed in augmented beats (4.9 ± 0.5 vs. 6.3 ± 0.8 m·s). Our findings show that IABP determined the pressure and smooth muscle-dependent changes in arterial wall energetics and damping properties in this animal model. ©2008Amercian Society of Artificial Internal Organs. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_10582916_v54_n1_p44_Fischer
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Cardiology Energy dissipation Physiological models Pressure effects Aortic pressure Aortic wall energetics Intra-aortic balloon pumping (IABP) Intra-aortic counterpulsation Biomechanics animal cell animal experiment animal model animal tissue aorta balloon aorta pressure aorta wall article biomechanics controlled study counterpulsation in vivo study mathematical computing nonhuman pulse wave sheep smooth muscle Animals Aorta Cardiac Output Cardiology Coronary Circulation Coronary Vessels Counterpulsation Disease Models, Animal Heart Failure Heart Rate Intra-Aortic Balloon Pumping Models, Biological Pressure Sheep Time Factors
spellingShingle	Cardiology Energy dissipation Physiological models Pressure effects Aortic pressure Aortic wall energetics Intra-aortic balloon pumping (IABP) Intra-aortic counterpulsation Biomechanics animal cell animal experiment animal model animal tissue aorta balloon aorta pressure aorta wall article biomechanics controlled study counterpulsation in vivo study mathematical computing nonhuman pulse wave sheep smooth muscle Animals Aorta Cardiac Output Cardiology Coronary Circulation Coronary Vessels Counterpulsation Disease Models, Animal Heart Failure Heart Rate Intra-Aortic Balloon Pumping Models, Biological Pressure Sheep Time Factors Fischer, E.I.C. Bia, D. Camus, J.M. Zócalo, Y. De Forteza, E. Armentano, R.L. Effects of intra-aortic counterpulsation on aortic wall energetics and damping: In vivo experiments
topic_facet	Cardiology Energy dissipation Physiological models Pressure effects Aortic pressure Aortic wall energetics Intra-aortic balloon pumping (IABP) Intra-aortic counterpulsation Biomechanics animal cell animal experiment animal model animal tissue aorta balloon aorta pressure aorta wall article biomechanics controlled study counterpulsation in vivo study mathematical computing nonhuman pulse wave sheep smooth muscle Animals Aorta Cardiac Output Cardiology Coronary Circulation Coronary Vessels Counterpulsation Disease Models, Animal Heart Failure Heart Rate Intra-Aortic Balloon Pumping Models, Biological Pressure Sheep Time Factors
description	Intra-aortic balloon pumping (IABP) could modify the arterial biomechanics; however, its effects on arterial wall properties have not been fully explored. This dynamical study was designed to characterize the pressure-dependent and smooth muscle-dependent effects of IABP on aortic wall energetics in an in vivo animal model. Intra-aortic balloon pumping (1:2) was performed in six anesthetized sheep in which aortic pressure and diameter signals were measured in basal, augmented (during balloon inflation), and assisted (postaugmented) beats. Energy dissipation values in augmented and assisted beats were significantly higher than those observed in basal state (p < 0.05). Assisted beats showed a significant increase of wall damping with respect to basal and augmented beats (p < 0.05). Intra-aortic balloon pumping resulted in a significant increase of pulse wave velocity (p < 0.05) in augmented beats with respect to basal state (6.3 ± 0.8 vs. 5.2 ± 0.5 m·s); whereas values observed in assisted beats were significantly (p < 0.05) lower than those observed in augmented beats (4.9 ± 0.5 vs. 6.3 ± 0.8 m·s). Our findings show that IABP determined the pressure and smooth muscle-dependent changes in arterial wall energetics and damping properties in this animal model. ©2008Amercian Society of Artificial Internal Organs.
format	JOUR
author	Fischer, E.I.C. Bia, D. Camus, J.M. Zócalo, Y. De Forteza, E. Armentano, R.L.
author_facet	Fischer, E.I.C. Bia, D. Camus, J.M. Zócalo, Y. De Forteza, E. Armentano, R.L.
author_sort	Fischer, E.I.C.
title	Effects of intra-aortic counterpulsation on aortic wall energetics and damping: In vivo experiments
title_short	Effects of intra-aortic counterpulsation on aortic wall energetics and damping: In vivo experiments
title_full	Effects of intra-aortic counterpulsation on aortic wall energetics and damping: In vivo experiments
title_fullStr	Effects of intra-aortic counterpulsation on aortic wall energetics and damping: In vivo experiments
title_full_unstemmed	Effects of intra-aortic counterpulsation on aortic wall energetics and damping: In vivo experiments
title_sort	effects of intra-aortic counterpulsation on aortic wall energetics and damping: in vivo experiments
url	http://hdl.handle.net/20.500.12110/paper_10582916_v54_n1_p44_Fischer
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Effects of intra-aortic counterpulsation on aortic wall energetics and damping: In vivo experiments

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