Disparities in pediatric leukemia early survival in Argentina: A population-based study

Objective. To identify disparities-using recursive partitioning (RP)-in early survival for children with leukemias treated in Argentina, and to depict the main characteristics of the most vulnerable groups. Methods. This secondary data analysis evaluated 12-month survival (12-ms) in 3 987 children d...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Garibotti, G., Moreno, F., Dussel, V., Orellana, L.
Formato:	JOUR
Materias:	Argentina Child Developing countries Healthcare disparities Leukemia Survival analysis cancer child health health care health survey national planning survival vulnerability adolescent age child developing country epidemiology female health care disparity human infant Kaplan Meier method lymphatic leukemia male mortality myeloid leukemia newborn preschool child prognosis proportional hazards model register sex difference socioeconomics survival rate Adolescent Age Factors Child, Preschool Developing Countries Female Healthcare Disparities Humans Infant Infant, Newborn Kaplan-Meier Estimate Leukemia, Lymphoid Leukemia, Myeloid Male Prognosis Proportional Hazards Models Registries Sex Factors Socioeconomic Factors Survival Rate
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_10204989_v36_n4_p248_Garibotti
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_10204989_v36_n4_p248_Garibotti
record_format	dspace
spelling	todo:paper_10204989_v36_n4_p248_Garibotti2023-10-03T15:56:33Z Disparities in pediatric leukemia early survival in Argentina: A population-based study Garibotti, G. Moreno, F. Dussel, V. Orellana, L. Argentina Child Developing countries Healthcare disparities Leukemia Survival analysis cancer child health health care health survey national planning survival vulnerability Argentina adolescent age Argentina child developing country epidemiology female health care disparity human infant Kaplan Meier method lymphatic leukemia male mortality myeloid leukemia newborn preschool child prognosis proportional hazards model register sex difference socioeconomics survival rate Adolescent Age Factors Argentina Child Child, Preschool Developing Countries Female Healthcare Disparities Humans Infant Infant, Newborn Kaplan-Meier Estimate Leukemia, Lymphoid Leukemia, Myeloid Male Prognosis Proportional Hazards Models Registries Sex Factors Socioeconomic Factors Survival Rate Objective. To identify disparities-using recursive partitioning (RP)-in early survival for children with leukemias treated in Argentina, and to depict the main characteristics of the most vulnerable groups. Methods. This secondary data analysis evaluated 12-month survival (12-ms) in 3 987 children diagnosed between 2000 and 2008 with lymphoid leukemia (LL) and myeloid leukemia (ML) and registered in Argentina's population-based oncopediatric registry. Prognostic groups based on age at diagnosis, gender, socioeconomic index of the province of residence, and migration to a different province to receive health care were identified using the RP method. Results. Overall 12-ms for LL and ML cases was 83.7% and 59.9% respectively. RP detected major gaps in 12-ms. Among 1-10-year-old LL patients from poorer provinces, 12-ms for those who did and did not migrate was 87.0% and 78.2% respectively. Survival of ML patients < 2 years old from provinces with a low/medium socioeconomic index was 38.9% compared to 62.1% for those in the same age group from richer provinces. For 2-14-year-old ML patients living in poor provinces, patient migration was associated with a 30% increase in 12-ms. Conclusions. Major disparities in leukemia survival among Argentine children were found. Patient migration and socioeconomic index of residence province were associated with survival. The RP method was instrumental in identifying and characterizing vulnerable groups. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_10204989_v36_n4_p248_Garibotti
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Argentina Child Developing countries Healthcare disparities Leukemia Survival analysis cancer child health health care health survey national planning survival vulnerability Argentina adolescent age Argentina child developing country epidemiology female health care disparity human infant Kaplan Meier method lymphatic leukemia male mortality myeloid leukemia newborn preschool child prognosis proportional hazards model register sex difference socioeconomics survival rate Adolescent Age Factors Argentina Child Child, Preschool Developing Countries Female Healthcare Disparities Humans Infant Infant, Newborn Kaplan-Meier Estimate Leukemia, Lymphoid Leukemia, Myeloid Male Prognosis Proportional Hazards Models Registries Sex Factors Socioeconomic Factors Survival Rate
spellingShingle	Argentina Child Developing countries Healthcare disparities Leukemia Survival analysis cancer child health health care health survey national planning survival vulnerability Argentina adolescent age Argentina child developing country epidemiology female health care disparity human infant Kaplan Meier method lymphatic leukemia male mortality myeloid leukemia newborn preschool child prognosis proportional hazards model register sex difference socioeconomics survival rate Adolescent Age Factors Argentina Child Child, Preschool Developing Countries Female Healthcare Disparities Humans Infant Infant, Newborn Kaplan-Meier Estimate Leukemia, Lymphoid Leukemia, Myeloid Male Prognosis Proportional Hazards Models Registries Sex Factors Socioeconomic Factors Survival Rate Garibotti, G. Moreno, F. Dussel, V. Orellana, L. Disparities in pediatric leukemia early survival in Argentina: A population-based study
topic_facet	Argentina Child Developing countries Healthcare disparities Leukemia Survival analysis cancer child health health care health survey national planning survival vulnerability Argentina adolescent age Argentina child developing country epidemiology female health care disparity human infant Kaplan Meier method lymphatic leukemia male mortality myeloid leukemia newborn preschool child prognosis proportional hazards model register sex difference socioeconomics survival rate Adolescent Age Factors Argentina Child Child, Preschool Developing Countries Female Healthcare Disparities Humans Infant Infant, Newborn Kaplan-Meier Estimate Leukemia, Lymphoid Leukemia, Myeloid Male Prognosis Proportional Hazards Models Registries Sex Factors Socioeconomic Factors Survival Rate
description	Objective. To identify disparities-using recursive partitioning (RP)-in early survival for children with leukemias treated in Argentina, and to depict the main characteristics of the most vulnerable groups. Methods. This secondary data analysis evaluated 12-month survival (12-ms) in 3 987 children diagnosed between 2000 and 2008 with lymphoid leukemia (LL) and myeloid leukemia (ML) and registered in Argentina's population-based oncopediatric registry. Prognostic groups based on age at diagnosis, gender, socioeconomic index of the province of residence, and migration to a different province to receive health care were identified using the RP method. Results. Overall 12-ms for LL and ML cases was 83.7% and 59.9% respectively. RP detected major gaps in 12-ms. Among 1-10-year-old LL patients from poorer provinces, 12-ms for those who did and did not migrate was 87.0% and 78.2% respectively. Survival of ML patients < 2 years old from provinces with a low/medium socioeconomic index was 38.9% compared to 62.1% for those in the same age group from richer provinces. For 2-14-year-old ML patients living in poor provinces, patient migration was associated with a 30% increase in 12-ms. Conclusions. Major disparities in leukemia survival among Argentine children were found. Patient migration and socioeconomic index of residence province were associated with survival. The RP method was instrumental in identifying and characterizing vulnerable groups.
format	JOUR
author	Garibotti, G. Moreno, F. Dussel, V. Orellana, L.
author_facet	Garibotti, G. Moreno, F. Dussel, V. Orellana, L.
author_sort	Garibotti, G.
title	Disparities in pediatric leukemia early survival in Argentina: A population-based study
title_short	Disparities in pediatric leukemia early survival in Argentina: A population-based study
title_full	Disparities in pediatric leukemia early survival in Argentina: A population-based study
title_fullStr	Disparities in pediatric leukemia early survival in Argentina: A population-based study
title_full_unstemmed	Disparities in pediatric leukemia early survival in Argentina: A population-based study
title_sort	disparities in pediatric leukemia early survival in argentina: a population-based study
url	http://hdl.handle.net/20.500.12110/paper_10204989_v36_n4_p248_Garibotti
work_keys_str_mv	AT garibottig disparitiesinpediatricleukemiaearlysurvivalinargentinaapopulationbasedstudy AT morenof disparitiesinpediatricleukemiaearlysurvivalinargentinaapopulationbasedstudy AT dusselv disparitiesinpediatricleukemiaearlysurvivalinargentinaapopulationbasedstudy AT orellanal disparitiesinpediatricleukemiaearlysurvivalinargentinaapopulationbasedstudy
_version_	1782027046369624064

Disparities in pediatric leukemia early survival in Argentina: A population-based study

Ejemplares similares