Interaction of cationic phthalocyanines with DNA. Importance of the structure of the substituents

The interaction of novel zinc (II) cationic phthalocyanines with CT-DNA was studied using absorption and fluorescence spectroscopy, as well as thermal denaturation profiles. Results showed an electrostatic interaction between the phthalocyanines and CT-DNA. The properties of these phthalocyanines we...

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Detalles Bibliográficos
Autores principales: López Zeballos, N.C., Gauna, G.A., García Vior, M.C., Awruch, J., Dicelio, L.E.
Formato: JOUR
Materias:
Aggregation
Calf thymus DNA
Fluorescence
Phthalocyanines
2,9(10),16(17),23(24) tetrakis [(n butyl n methylammonium)ethylsulfanyl]phthalocyaninatozinc(II) tetraiodide
2,9(10),16(17),23(24) tetrakis[(2 trimethylammonium)ethyl sulfanyl]phthalocyaninatozinc(II) tetraioide
2,9(10),16(17),23(24) tetrakis[(n dibutyl n methylammonium)ethoxy]phthalocyaninatozinc(II) tetraiodide
cation
DNA
dye
iodide
macrocyclic compound
phthalocyanine
sulfur
trimethylammonium salt derivative
unclassified drug
zinc
calf thymus DNA
indole derivative
absorption
article
binding affinity
chemical structure
denaturation
DNA binding
DNA helix
fluorescence spectroscopy
priority journal
static electricity
thymus
chemistry
DNA denaturation
heat
spectrofluorometry
ultraviolet spectrophotometry
Cations
Hot Temperature
Indoles
Nucleic Acid Denaturation
Spectrometry, Fluorescence
Spectrophotometry, Ultraviolet
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_10111344_v136_n_p29_LopezZeballos
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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