Parental age influences developmental stability of the progeny in Drosophila
The stochastic nature of biochemical processes is a source of variability that influences developmental stability. Developmental instability (DI) is often estimated through fluctuating asymmetry (FA), a parameter that deals with within-individual variation in bilateral structures. A relevant goal is...
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| Formato: | JOUR |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_09628452_v282_n1803_p_Colines |
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todo:paper_09628452_v282_n1803_p_Colines2023-10-03T15:54:19Z Parental age influences developmental stability of the progeny in Drosophila Colines, B. Rodríguez, N.C. Hasson, E.R. Carreira, V. Frankel, N. Developmental instability Diet Drosophila Fluctuating asymmetry Inbreeding Parental age age biochemical composition developmental biology diet fluctuating asymmetry fly genotype heterogeneity inbreeding parameterization Drosophila melanogaster The stochastic nature of biochemical processes is a source of variability that influences developmental stability. Developmental instability (DI) is often estimated through fluctuating asymmetry (FA), a parameter that deals with within-individual variation in bilateral structures. A relevant goal is to shed light on how environment, physiology and genotype relate to DI, thus providing a more comprehensive view of organismal development. Using Drosophila melanogaster isogenic lines, we investigated the effect of parental age, parental diet and offspring heterozygosity on DI. In this work, we have uncovered a clear relationship between parental age and offspring asymmetry. We show that asymmetry of the progeny increases concomitantly with parental age. Moreover, we demonstrate that enriching the diet of parents mitigates the effect of age on offspring symmetry. We show as well that increasing the heterozygosity of the progeny eliminates the effect of parental age on offspring symmetry. Taken together, our results suggest that diet, genotype and age of the parents interact to determine offspring DI in wild populations. These findings provide us with an avenue to understand the mechanisms underlying DI. ©2015 The Author(s) Published by the Royal Society. All rights reserved. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_09628452_v282_n1803_p_Colines |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Developmental instability Diet Drosophila Fluctuating asymmetry Inbreeding Parental age age biochemical composition developmental biology diet fluctuating asymmetry fly genotype heterogeneity inbreeding parameterization Drosophila melanogaster |
| spellingShingle |
Developmental instability Diet Drosophila Fluctuating asymmetry Inbreeding Parental age age biochemical composition developmental biology diet fluctuating asymmetry fly genotype heterogeneity inbreeding parameterization Drosophila melanogaster Colines, B. Rodríguez, N.C. Hasson, E.R. Carreira, V. Frankel, N. Parental age influences developmental stability of the progeny in Drosophila |
| topic_facet |
Developmental instability Diet Drosophila Fluctuating asymmetry Inbreeding Parental age age biochemical composition developmental biology diet fluctuating asymmetry fly genotype heterogeneity inbreeding parameterization Drosophila melanogaster |
| description |
The stochastic nature of biochemical processes is a source of variability that influences developmental stability. Developmental instability (DI) is often estimated through fluctuating asymmetry (FA), a parameter that deals with within-individual variation in bilateral structures. A relevant goal is to shed light on how environment, physiology and genotype relate to DI, thus providing a more comprehensive view of organismal development. Using Drosophila melanogaster isogenic lines, we investigated the effect of parental age, parental diet and offspring heterozygosity on DI. In this work, we have uncovered a clear relationship between parental age and offspring asymmetry. We show that asymmetry of the progeny increases concomitantly with parental age. Moreover, we demonstrate that enriching the diet of parents mitigates the effect of age on offspring symmetry. We show as well that increasing the heterozygosity of the progeny eliminates the effect of parental age on offspring symmetry. Taken together, our results suggest that diet, genotype and age of the parents interact to determine offspring DI in wild populations. These findings provide us with an avenue to understand the mechanisms underlying DI. ©2015 The Author(s) Published by the Royal Society. All rights reserved. |
| format |
JOUR |
| author |
Colines, B. Rodríguez, N.C. Hasson, E.R. Carreira, V. Frankel, N. |
| author_facet |
Colines, B. Rodríguez, N.C. Hasson, E.R. Carreira, V. Frankel, N. |
| author_sort |
Colines, B. |
| title |
Parental age influences developmental stability of the progeny in Drosophila |
| title_short |
Parental age influences developmental stability of the progeny in Drosophila |
| title_full |
Parental age influences developmental stability of the progeny in Drosophila |
| title_fullStr |
Parental age influences developmental stability of the progeny in Drosophila |
| title_full_unstemmed |
Parental age influences developmental stability of the progeny in Drosophila |
| title_sort |
parental age influences developmental stability of the progeny in drosophila |
| url |
http://hdl.handle.net/20.500.12110/paper_09628452_v282_n1803_p_Colines |
| work_keys_str_mv |
AT colinesb parentalageinfluencesdevelopmentalstabilityoftheprogenyindrosophila AT rodrigueznc parentalageinfluencesdevelopmentalstabilityoftheprogenyindrosophila AT hassoner parentalageinfluencesdevelopmentalstabilityoftheprogenyindrosophila AT carreirav parentalageinfluencesdevelopmentalstabilityoftheprogenyindrosophila AT frankeln parentalageinfluencesdevelopmentalstabilityoftheprogenyindrosophila |
| _version_ |
1807319663882797056 |