Growth inhibitory effect of juvenile hormone analogues on epimastigotes of Trypanosoma cruzi

Several compounds, structurally related to the insect growth regulator Fenoxycarb, exhibited interesting inhibition action to control proliferation of Trypanosoma cruzi, the parasite responsible for Chagas' disease. Some of these drugs were shown to be potent growth inhibitors of this parasite....

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Rodriguez, J.B., Zhong, L., Docampo, R., Wimmer, Z., Gros, E.G.
Formato: JOUR
Materias:
benznidazole
fenoxycarb
hormone analog
ketoconazole
nifurtimox
article
drug mechanism
drug structure
epimastigote
growth inhibition
nonhuman
structure activity relation
Trypanosoma cruzi
Dysdercus
Galleria mellonella
Insecta
Pyrrhocoris apterus
Tenebrio molitor
Trypanosoma
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0960894X_v8_n22_p3257_Rodriguez
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_0960894X_v8_n22_p3257_Rodriguez
record_format dspace
spelling todo:paper_0960894X_v8_n22_p3257_Rodriguez2023-10-03T15:54:04Z Growth inhibitory effect of juvenile hormone analogues on epimastigotes of Trypanosoma cruzi Rodriguez, J.B. Zhong, L. Docampo, R. Wimmer, Z. Gros, E.G. benznidazole fenoxycarb hormone analog ketoconazole nifurtimox article drug mechanism drug structure epimastigote growth inhibition nonhuman structure activity relation Trypanosoma cruzi Dysdercus Galleria mellonella Insecta Pyrrhocoris apterus Tenebrio molitor Trypanosoma Trypanosoma cruzi Several compounds, structurally related to the insect growth regulator Fenoxycarb, exhibited interesting inhibition action to control proliferation of Trypanosoma cruzi, the parasite responsible for Chagas' disease. Some of these drugs were shown to be potent growth inhibitors of this parasite. All of these drugs had previously presented juvenoid activity on several non- related bug species such as Tenebrio molitor, Galleria mellonella, Dysdercus cingulatos, and Pyrrhocoris apterus. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_0960894X_v8_n22_p3257_Rodriguez
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic benznidazole
fenoxycarb
hormone analog
ketoconazole
nifurtimox
article
drug mechanism
drug structure
epimastigote
growth inhibition
nonhuman
structure activity relation
Trypanosoma cruzi
Dysdercus
Galleria mellonella
Insecta
Pyrrhocoris apterus
Tenebrio molitor
Trypanosoma
Trypanosoma cruzi
spellingShingle benznidazole
fenoxycarb
hormone analog
ketoconazole
nifurtimox
article
drug mechanism
drug structure
epimastigote
growth inhibition
nonhuman
structure activity relation
Trypanosoma cruzi
Dysdercus
Galleria mellonella
Insecta
Pyrrhocoris apterus
Tenebrio molitor
Trypanosoma
Trypanosoma cruzi
Rodriguez, J.B.
Zhong, L.
Docampo, R.
Wimmer, Z.
Gros, E.G.
Growth inhibitory effect of juvenile hormone analogues on epimastigotes of Trypanosoma cruzi
topic_facet benznidazole
fenoxycarb
hormone analog
ketoconazole
nifurtimox
article
drug mechanism
drug structure
epimastigote
growth inhibition
nonhuman
structure activity relation
Trypanosoma cruzi
Dysdercus
Galleria mellonella
Insecta
Pyrrhocoris apterus
Tenebrio molitor
Trypanosoma
Trypanosoma cruzi
description Several compounds, structurally related to the insect growth regulator Fenoxycarb, exhibited interesting inhibition action to control proliferation of Trypanosoma cruzi, the parasite responsible for Chagas' disease. Some of these drugs were shown to be potent growth inhibitors of this parasite. All of these drugs had previously presented juvenoid activity on several non- related bug species such as Tenebrio molitor, Galleria mellonella, Dysdercus cingulatos, and Pyrrhocoris apterus.
format JOUR
author Rodriguez, J.B.
Zhong, L.
Docampo, R.
Wimmer, Z.
Gros, E.G.
author_facet Rodriguez, J.B.
Zhong, L.
Docampo, R.
Wimmer, Z.
Gros, E.G.
author_sort Rodriguez, J.B.
title Growth inhibitory effect of juvenile hormone analogues on epimastigotes of Trypanosoma cruzi
title_short Growth inhibitory effect of juvenile hormone analogues on epimastigotes of Trypanosoma cruzi
title_full Growth inhibitory effect of juvenile hormone analogues on epimastigotes of Trypanosoma cruzi
title_fullStr Growth inhibitory effect of juvenile hormone analogues on epimastigotes of Trypanosoma cruzi
title_full_unstemmed Growth inhibitory effect of juvenile hormone analogues on epimastigotes of Trypanosoma cruzi
title_sort growth inhibitory effect of juvenile hormone analogues on epimastigotes of trypanosoma cruzi
url http://hdl.handle.net/20.500.12110/paper_0960894X_v8_n22_p3257_Rodriguez
work_keys_str_mv AT rodriguezjb growthinhibitoryeffectofjuvenilehormoneanaloguesonepimastigotesoftrypanosomacruzi
AT zhongl growthinhibitoryeffectofjuvenilehormoneanaloguesonepimastigotesoftrypanosomacruzi
AT docampor growthinhibitoryeffectofjuvenilehormoneanaloguesonepimastigotesoftrypanosomacruzi
AT wimmerz growthinhibitoryeffectofjuvenilehormoneanaloguesonepimastigotesoftrypanosomacruzi
AT groseg growthinhibitoryeffectofjuvenilehormoneanaloguesonepimastigotesoftrypanosomacruzi
_version_ 1807316784487858176

Ejemplares similares