Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi

Several derivatives of geraniol, geranylacetone, and farnesol bearing carbonate and thiolcarbonate functional groups as well as several derivatives of 4-phenoxyphenol were synthesized and tested for their respective biological activity as growth inhibitors for Trypanosoma cruzi, and for inhibition o...

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Autores principales: Rodriguez, J.B., Gros, E.G., Stoka, A.M.
Formato: JOUR
Materias:
juvenile hormone derivative
methoprene
article
cytotoxicity
dna synthesis
nonhuman
trypanosoma cruzi
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0960894X_v1_n12_p679_Rodriguez
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
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spelling todo:paper_0960894X_v1_n12_p679_Rodriguez2023-10-03T15:54:00Z Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi Rodriguez, J.B. Gros, E.G. Stoka, A.M. juvenile hormone derivative methoprene article cytotoxicity dna synthesis nonhuman trypanosoma cruzi Several derivatives of geraniol, geranylacetone, and farnesol bearing carbonate and thiolcarbonate functional groups as well as several derivatives of 4-phenoxyphenol were synthesized and tested for their respective biological activity as growth inhibitors for Trypanosoma cruzi, and for inhibition of tritium-labelled thymidine incorporation in T. cruzi cells. The results indicated that some JHA showed important activity against the development of the cells. © 1991. Fil:Rodriguez, J.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Gros, E.G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Stoka, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_0960894X_v1_n12_p679_Rodriguez
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic juvenile hormone derivative
methoprene
article
cytotoxicity
dna synthesis
nonhuman
trypanosoma cruzi
spellingShingle juvenile hormone derivative
methoprene
article
cytotoxicity
dna synthesis
nonhuman
trypanosoma cruzi
Rodriguez, J.B.
Gros, E.G.
Stoka, A.M.
Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi
topic_facet juvenile hormone derivative
methoprene
article
cytotoxicity
dna synthesis
nonhuman
trypanosoma cruzi
description Several derivatives of geraniol, geranylacetone, and farnesol bearing carbonate and thiolcarbonate functional groups as well as several derivatives of 4-phenoxyphenol were synthesized and tested for their respective biological activity as growth inhibitors for Trypanosoma cruzi, and for inhibition of tritium-labelled thymidine incorporation in T. cruzi cells. The results indicated that some JHA showed important activity against the development of the cells. © 1991.
format JOUR
author Rodriguez, J.B.
Gros, E.G.
Stoka, A.M.
author_facet Rodriguez, J.B.
Gros, E.G.
Stoka, A.M.
author_sort Rodriguez, J.B.
title Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi
title_short Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi
title_full Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi
title_fullStr Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi
title_full_unstemmed Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi
title_sort synthesis and biological activivity of juvenele hormone analogues (jha) for trypanosoma cruzi
url http://hdl.handle.net/20.500.12110/paper_0960894X_v1_n12_p679_Rodriguez
work_keys_str_mv AT rodriguezjb synthesisandbiologicalactivivityofjuvenelehormoneanaloguesjhafortrypanosomacruzi
AT groseg synthesisandbiologicalactivivityofjuvenelehormoneanaloguesjhafortrypanosomacruzi
AT stokaam synthesisandbiologicalactivivityofjuvenelehormoneanaloguesjhafortrypanosomacruzi
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